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A CASE OF COMPLETE RECOVERY OF DISSEMINATED RENAL ALLOGRAFT TUMOR

https://doi.org/10.17650/1726-9776-2010-6-2-63-68

Abstract

Rhabdomyosarcoma is the most common soft tissue tumor in children aged less than 19 years. In the represented case report, polychemotherapy at Stage 1 of treatment resulted in a complete regression of metastases in the lung and pleura, normalization of the patients health status within 18 months. Consolidation radiotherapy directed to the prostate and femoral bones could achieve a local control over these foci. The emerged recurrence was located in the lung and pleura. The effect of second-line chemotherapy did not exceed 3 months. Despite primary disease dissemination and poor prognosis, disease stabilization and better quality of life (improved general condition, recovery of spontaneous urination, relief and complete disappearance of pain) could be achieved at therapy month 27.

About the Authors

O. B. Karyakin
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


S. V. Bashkatov
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


O. V. Terekhov
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


D. V. Neledov
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


N. A. Gorban
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


Yu. V. Gumenetskaya
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


E. A. Donichkina
Medical radiology research center, Russian academy of medical sciences, Obninsk
Russian Federation


References

1. Gurney J.G., Young J.L., Roffers S.D. et al. Soft tissue sarcomas. In: Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. Ries L.A.G., Smith M.A.,Gurney J.G. et al. eds. SEER Program, NIH Pub. 99-4649. Bethesda, MD, National Cancer Institute, 1999.

2. Maurer H.M., Gehan E.A., Beltangady M. et al. The Intergroup Rhabdomyosarcoma Study-II. Cancer 1993;71:1904-22.

3. Maurer H.M., Beltangady M.,Gehan E.A. et al. The Intergroup Rhabdomyosarcoma Study-I. A final report. Cancer 1988;61:209-20.

4. Crist W., Gehan E.A., Ragab A.H. et al. The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 1995;13:610-30.

5. Green D.M., Jaffe N. Progress and controversy in the treatment of childhood rhabdomyosarcoma. Cancer Treatment Rev 1978;5(1):7-27.

6. Wiltshaw E., Gowing N.F., Stuart-Harris R. et al. Chemotherapy of endodermal sinus tumour (yolk sac tumour) of the ovary: preliminary communication. J R Soc Med 1982;75(11)888-92.

7. Bode U. Methotrexate as relapse therapy for rhabdomyosarcoma. Am J Pediatr Hematol Oncol 1986;8(1):70-2.

8. Horowitz M.E., Etcubanas E.,Christensen M.L. et al. Phase II testing of melphalan in children with newly diagnosed rhabdomyosarcoma: a model for anticancer drug development. J Clin Oncol1988;6(2):308-14.

9. Otten J., Flamant F., Rodary C. et al. Treatment of rhabdomyosarcoma and other malignant mesenchymal tumours of childhood with ifosfamide + vincristine + dactinomycin (IVA) as front-line therapy (a SIOP study). Cancer Chemoter Pharmacol 1989;24 Suppl:30.


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For citations:


Karyakin O.B., Bashkatov S.V., Terekhov O.V., Neledov D.V., Gorban N.A., Gumenetskaya Yu.V., Donichkina E.A. A CASE OF COMPLETE RECOVERY OF DISSEMINATED RENAL ALLOGRAFT TUMOR. Cancer Urology. 2010;6(2):63-68. (In Russ.) https://doi.org/10.17650/1726-9776-2010-6-2-63-68

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ISSN 1726-9776 (Print)
ISSN 1996-1812 (Online)
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