Intermediate results of the observational program on the Eligard (45 mg) administration in the clinical practice
https://doi.org/10.17650/1726-9776-2016-12-2-84-91
Abstract
This article deals with the intermediate results of the multicentral observational program on the 6-month prodrug leuprorelin acetate (Eligard 45 mg) administration. The study objective is to confirm the efficiency and safety of the Eligard 45 mg administration in patients with the prostate cancer in the clinical practice of the oncourology specialists in Russia. In 12 months of the hormone therapy with the Eligard 45 mg there was the clinically relevant decrease of the prostatic specific antigen (PSA) levels secondary to the appropriate suppression of the testosterone level lower than the castration one < 20 ng / dl. The PSA level decreased, at an average, on 82 % (from 41.4 to 7.65 ng / ml). In 89 % of patients, treated with Eligard 45 mg, the testosterone level was < 20 ng / dl. The patients», treated with Eligard 45 mg, quality of life analysis showed the improvement of this criteria in the course of the treatment. Thus, intermediate results of the multicentral observational program, proved the favorable tolerability and efficiency of the 6-month prodrug Eligard 45 mg towards the PSA and testosterone serum levels suppression in the routine clinical practice in prostate cancer patients.
About the Authors
V. B. Matveev
N.N. Blokhin Russian Cancer Research Center; 23 Kashirskoe Shosse, Moscow, 115478, Russia
Russian Federation
Russian Federation
A. S. Markova
N.N. Blokhin Russian Cancer Research Center; 23 Kashirskoe Shosse, Moscow, 115478, Russia
Russian Federation
Russian Federation
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For citations:
Matveev V.B., Markova A.S. Intermediate results of the observational program on the Eligard (45 mg) administration in the clinical practice. Cancer Urology. 2016;12(2):84-91. https://doi.org/10.17650/1726-9776-2016-12-2-84-91
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