EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN ADENOCARCINOMA OF PROSTATE
https://doi.org/10.17650/1726-9776-2014-10-2-35-37
Abstract
Iimmunohistochemical study of cells proliferative activity by Ki-67 protein and localization of matrix metalloproteinase-9 (MMP-9) has been carried out at benign prostatic hyperplasia and adenocarcinoma of different gradations by the Gleason score. A significant decrease of the MMP-9 levels in the adenocarcinoma of different gradations have been found. A moderate positive correlation between the Gleason score and cell proliferation Ki-67 index (rs = 0.674) and a moderate negative correlation with the level of such score and expression of MMP-9 (rs = –0.660) were detected
About the Authors
M. I. Andruchin
Peoples’ Friendship University of Russia, Moscow
Russian Federation
Department of Urology and Operative Nephrology
Russian Federation
Department of Urology and Operative Nephrology
S. A. Pulbere
Peoples’ Friendship University of Russia, Moscow
Russian Federation
Department of Urology and Operative Nephrology
Russian Federation
Department of Urology and Operative Nephrology
A. V. Loktev
Peoples’ Friendship University of Russia, Moscow
Russian Federation
Department of Urology and Operative Nephrology
Russian Federation
Department of Urology and Operative Nephrology
I. I. Babichenko
Peoples’ Friendship University of Russia, Moscow
Russian Federation
Department of Pathological Anatomy
Russian Federation
Department of Pathological Anatomy
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Review
For citations:
Andruchin M.I., Pulbere S.A., Loktev A.V., Babichenko I.I. EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN ADENOCARCINOMA OF PROSTATE. Cancer Urology. 2014;10(2):35-37. (In Russ.) https://doi.org/10.17650/1726-9776-2014-10-2-35-37
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