Paraneoplastic syndrome in urothelial carcinoma of the kidney: difficulty in diagnosis and deterioration in prognosis
https://doi.org/10.17650/1726-9776-2015-11-3-46-49
Abstract
Paraneoplastic syndrome is not a common concomitance of urothelial tumors. The literature describes a few tens of clinical cases in which urothelial cancer has become a cause of marked nonspecific tumor-associated reactions, associated with the presence of the tumor. Bladder tumors are at stake in all cases. The given clinical observation describes paraneoplastic manifestations in high-grade urothelial carcinoma of the kidney. It demonstrates difficulties in differential diagnosis and gives a retrospective estimate of diagnostic and therapeutic tactics.
About the Authors
I. E. Mamaev
1Department of Urology, City Clinical Hospital Twelve, Moscow Healthcare Department; 26, Bakinskaya St., Moscow 115516, Russia
Department of Urology, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; 1, Ostrovityanov St., Moscow 117997, Russia
Russian Federation
Russian Federation
A. Yu. Seroukhov
1Department of Urology, City Clinical Hospital Twelve, Moscow Healthcare Department; 26, Bakinskaya St., Moscow 115516, Russia
Russian Federation
Russian Federation
K. I. Glinin
1Department of Urology, City Clinical Hospital Twelve, Moscow Healthcare Department; 26, Bakinskaya St., Moscow 115516, Russia
Russian Federation
Russian Federation
E. A. Pronkin
Department of Urology, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; 1, Ostrovityanov St., Moscow 117997, Russia
Russian Federation
Russian Federation
References
1. Дворецкий Л.И. Паранеопластические синдромы. Consilium medicum 2003;3(3). [Dvoretckii L.I. Paraneoplastic syndromes. Consilium medicum 2003;3(3). (In Russ.)].
2. Sacco E., Pinto F., Sasso F. et al. Paraneoplastic syndromes in patients with urological malignancies. Urol Int 2009;83: 1–11.
3. Palapattu G.S., Kristo B., Rajfer J. Paraneoplastic syndromes in urologic malignancy: the many faces of renal cell carcinoma. Rev Urol 2002;4(4):163–70.
4. Izard J.P., Gore J.L., Mostaghel E.A. et al. Persistent, unexplained leukocytosis is a paraneoplastic syndrome associated with a poor prognosis in patients with urothelial carcinoma. Clin Genitourin Cancer 2015;13(4):e253-8. doi: 10.1016/j. clgc.2015.02.008.
5. Francisco A. Perez, Corinne L. Fligner, Evan Y. Yu, Rapid clinical deterioration and leukemoid reaction after treatment of urothelial carcinoma of the bladder: possible effect of granulocyte colony-stimulating factor. JCO 2009;1:e215-e217.
6. Suo A., Abbas T. Paraneoplastic leukemoid reaction in a patient with urothelial carcinoma: a case report. CRCM 2014;3:249–52.
7. Zell J.A., Chang J.C. Neoplastic fever: a neglected paraneoplastic syndrome. SCC 2005;13(11):870–7.
8. Jung J.S., Lee S.M., Kim H.J. et al. A case of septic pulmonary embolism associated with renal abscess mimicking pulmonary metastases of renal malignancy. Ann Nucl Med 2014; 28(4): 381–5.
9. Penel N., Fournier C., Degardin M. et al. Fever and solid tumor: diagnostic value of procalcitonin and C-reactive protein. Rev Med Interne 2001;22(8): 706–14.
Review
For citations:
Mamaev I.E., Seroukhov A.Yu., Glinin K.I., Pronkin E.A. Paraneoplastic syndrome in urothelial carcinoma of the kidney: difficulty in diagnosis and deterioration in prognosis. Cancer Urology. 2015;11(3):46-49. (In Russ.) https://doi.org/10.17650/1726-9776-2015-11-3-46-49
Views:
2443
Email this article 