Testicular rabdomiosarkoma in children: 19 years of experience
https://doi.org/10.17650/1726-9776-2014-10-3-78-82
Abstract
From 1990 to 2009, at the Research Institute of Children Oncology and Hematology have undergone examination and treatment 26 children with paratesticular rhabdomyosarcoma. The average age of our patients was 6.2 years (range 3 months to 15 years). All children was performed tumor markers level evaluation and ultrasound. In 6 children identified metastases. Surgical treatment is the first stage in the volume of orchifunikulektomia was held in 26 children. Retroperitoneal limfoadenektomiya was performed in 4 children and 1 child undergone thoracotomy with removal of metastases in the lung. Drug treatment was performed in 26 children with paratesticular rhabdomyosarcoma tumor. Using a combined method of treatment of malignant tumors led to 92.3 % overall survival.
About the Authors
M. A. RokhoevRussian Federation
I. V. Nechushkina
Russian Federation
E. V. Mikhaylova
Russian Federation
O. A. Kapkova
Russian Federation
D. B. Khestanov
Russian Federation
K. O. Khaphizov
Russian Federation
References
1. Coleman J., Brennan M., Alektiar K., Russo P. Adult spermatic cord sarcomas: management and results. Ann Surg Oncol 2003;10: 669–75.
2. Katiku K., Esho J.O., Azodo M.V.U. Paratesticular Rhabdomyosarcoma in adolescents. Euro Urol 1988;14:245–8.
3. Stewart L.H., Lioc T.F., Johnston S.R. Thirty year of intra scrotal rhabdomyosarcoma. Br J Urol 1991;68:418–20.
4. Sygder II H.M., Dangio G.J., Evans A.E. et al. Pediatric oncology in Campbell’s urology, 7th ed., Philadelphia: WB Saunders, 1998.
5. Slama A., Jaidane M., Ben Sorba N. et al. Le rhabdomyosarcome paratesticulaire. Prog Urol 2000;10:1232–4.
6. McDowell H.P. Update on childhood rhabdomyosarcoma. Arch Dis Child 2003;88:354–7.
7. Newton W.A. Gehan E.A., Webber B.L. et al. Classification of rhabdomyosarcоmas and related sarcomas. Pathologic aspects and proposal for a new classification an Intergroup Rhabdomyosarcoma Study. Cancer 1995;76:1073–85.
8. Ferrari A., Casanova M., Massimino M. et al. The management of paratesticular rhabdomyosarcoma a single institutional experience with 44 consecutive children. J Urol 1998;159:1031–4.
9. Masson J.C., Varini J.P., Masson J. et al. Sarcomes du cordon spermatique: rapport de 2 cas. Revue de la litte´rature. Prog Urol 1992;2:272–81.
10. Olives D., Flamant F., Zucker J.M. et al. Paraaortic lymphadenectomy is not necessary in the treatment of localized paratesticular rhabdomyosarcoma. Cancer 1984;54:1283–7. 11. Anderson J.R., Ruby E., Link M. Identification of a favorable subset of patients with metastatic rhabdomyosarcoma. Proc Am Soc Clin Oncol 1997;16:abstr.
11. Meza J.L., Anderson J., Pappo A.S. et al. Analysis of prognostic factors in patients with nonmetastatic rhabdomyosarcoma treated on intergroup rhabdomyosarcoma studies III and IV: the children’s oncology group. J Clin Oncol 2006;24:3844–51.
12. Benson C.B., Doubilet P.M., Richie J.P. Sonography of the male genital tract. AJR 1989;153:705–13.
13. Stevens M.C., Rey A., Bouvet N. et al. Treatment of nonmetastatic rhabdomyosarcoma in childhood and adolescence: third study of the nternational society of paediatric oncology–SIOP malignant mesenchymal tumor 89. J Clin Oncol 2005;23: 2618–28.
14. Михайлова Е.В. Ультразвуковая диагностика опухолей яичка у детей. Автореф. дис. … канд. мед. наук. М., 2007.
15. Akbar S.A., Sayyed T.A., Jafri S.Z. et al. Multimodality imaging of paratesticular neoplasms and their rare mimics. Radiographics 2003;23:1461–76.
Review
For citations:
Rokhoev M.A., Nechushkina I.V., Mikhaylova E.V., Kapkova O.A., Khestanov D.B., Khaphizov K.O. Testicular rabdomiosarkoma in children: 19 years of experience. Cancer Urology. 2014;10(3):78-82. (In Russ.) https://doi.org/10.17650/1726-9776-2014-10-3-78-82