DIAGNOSIS OF NON-MUSCLE-INVASIVE PAPILLARY BLADDER TUMORS: CLASSIFICATIONAL AND MORPHOLOGICAL ASPECTS
https://doi.org/10.17650/1726-9776-2014-10-2-12-15
Abstract
The diagnosis of superficial papillary bladder tumors remains a serious problem and has 2 aspects: classificational and morphological ones. As of now, 2 classifications of superficial bladder tumors, the basis for which is different principles (the 1973 WHO and the 2004 WHO ones) are equally used. Pathologists and clinicians must know criteria for both classifications and understand their differences, advantages, and disadvantages. If they are unaware of the normal structure of the bladder and the specific features of work with transurethral resection material, they cannot adequately stage non-muscle-invasive tumors.
About the Authors
N. A. Gorban
Medical Radiology Research Center, Obninsk
Russian Federation
Russian Federation
V. V. Pugachev
Medical Radiology Research Center, Obninsk
Russian Federation
Russian Federation
O. B. Karyakin
Medical Radiology Research Center, Obninsk
Russian Federation
Russian Federation
References
1. Мостофи Ф.К., Собин Л.Г., Торлони Г. и др. Гистологическая классификация опухолей мочевого пузыря. Женева: ВОЗ, 1977. 35 с.
2. World Health Organization Classification of Tumours. Pathology & Genetics: Tumours of the Urinary System and Male Genital Organs. Lyon, France: IARC Press, 2004.
3. Mostofi F.K. Pathological aspects and spread of carcinoma of the bladder. JAMA 1968;206(8):1764–9.
4. Miyamoto H., Miller J.S., Fajardo D.A. et al. Non-invasive papillary urothelial neoplasms: the 2004 WHO/ISUP classification system. Pathol Int 2010;60(1):1–8. Erratum in: Pathol Int 2010;60(2):147.
5. Simon R., Bьrger H., Brinkschmidt C. et al. Chromosomal aberrations associated with invasion in papillary superficial bladder cancer. J Pathol 1998;185(4):345–51.
6. Lopez-Beltran A., Cheng L., Mazzucchelli R. et al. Morphological and molecular profiles and pathways in bladder neoplasms. Anticancer Res 2008;28(5B):2893–900.
7. Hofmann T., Knuchel-Clarke R., Hartmann A. et al. Clinucal Implications of the 2004 WHO Histological Classification on Non-Invasive Tumours of the Urinary Bladder. EAU-EBU Update Series 4 (2004):83–95.
8. Montironi R., Lopez-Beltran A., Scarpelli M. et al. Morphological classification and definition of benign, preneoplastic and non-invasive neoplastic lesions of the urinary bladder. Histopathology 2008;53(6):621–33.
9. Montironi R., Mazzucchelli R., Scarpelli M. et al. Morphological diagnosis of urothelial neoplasms. J Clin Pathol 2008;61(1):3–10.
10. MacLennan G.T., Kirkali Z., Cheng L. Histologic grading of noninvasive papillary uro-thelial neoplasms. Eur Urol 2007;51(4):889–97.
11. May M., Brookman-Amissah S., Roigas J. et al. Prognostic accuracy of individual uropathologists in noninvasive urinary bladder carcinoma: a multicentre study comparing the 1973 and 2004 World Health Organisation classifications. Eur Urol 2010;57(5):850–8.
12. Lopez-Beltran A., Montironi R. Non-invasive urothelial neoplasms: according to the most recent WHO classification. Eur Urol 2004;46(2):170–6.
13. Montironi R., Cheng L., Scarpelli M. et al. How much do you know about benign, preneoplastic, non-invasive and invasive neoplastic lesions of the urinary bladder classified according to the 2004 WHO scheme? Diagn Pathol 2011;6:31.
14. Cheng L., Montironi R., Davidson D.D., Lopez-Beltran A. Staging and reporting of urothelial carcinoma of the urinary bladder. Mod Pathol 2009;22(Suppl 2):70–95.
15. Pan C.C., Chang Y.H., Chen K.K. et al. Prognostic significance of the 2004 WHO/ISUP classification for prediction of recurrence, progression, and cancer-specific mortality of non-muscle-invasive urothelial tumors of the urinary bladder: a clinicopathologic study of 1,515 cases. Am J Clin Pathol 2010;133(5):788–95.
16. Petersen R.O., Sesterhenn I.A., Davis C.J. Urologic Pathology. Lippincott Williams & Wilkins, 2009. 636 p.
Review
For citations:
Gorban N.A., Pugachev V.V., Karyakin O.B. DIAGNOSIS OF NON-MUSCLE-INVASIVE PAPILLARY BLADDER TUMORS: CLASSIFICATIONAL AND MORPHOLOGICAL ASPECTS. Cancer Urology. 2014;10(2):12-15. (In Russ.) https://doi.org/10.17650/1726-9776-2014-10-2-12-15
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