ВЗАИМОСВЯЗЬ ПРОСТАТИЧЕСКИХ КАМНЕЙ И РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ
https://doi.org/10.17650/1726-9776-2012-8-3-72-75
Abstract
The impact of prostatoliths (PL) on the level of prostate-specific antigen (PSA) was evaluated and their association with prostate cancer (PC) was studied in 145 patients with benign hyperplasia and cancer of the prostate. No statistically significant increase in PSA levels in the presence of PL was found. A chronic inflammatory process in the prostate was more common in PC concurrent with PL, which is an indirect sign
of a possible correlation between PL and PC. Final conclusions about the oncourological aspects of PL can be made only after further investigations in this area.
About the Authors
F. I. GuseinovRussian Federation
A. Z. Vinarov
Russian Federation
References
1. Мохаммед Абдул Кашем Шакар. Камни предстательной железы (этиология, кинетика, диагностика и лечение). Дис. … канд. мед. наук. М., 1989. 238 с.
2. Park S.-W., Nam J.-K., Lee S.-D., Chung M.-K. Are prostatic calculi independent predictive factors of lower urinary tract symptoms? /Asian J Andrology 2010;12(2):221–6.
3. Geramoutsos I., Gyftopoulos K., Perimenis P. et al. Clinical correlation of prostatic lithiasis with chronic pelvic pain syndromes in young adults. Eur Urol 2004;45(3):333–7.
4. Köseoğlu H., Aslan G., Sen B.H. et al. Prostatic calculi: silent stones. Actas Urol Esp 2010;34(6):555−9.
5. Chen H.J., Yang N.G., Zhang J.J., Wang J. et al. Relationship between chronic prostatitis and prostatic calculus. Zhonghua Nan KeXue 2011;17(1): 43−6.
6. Nelson W.G., De Marzo A.M., DeWeese T.L., Isaacs W.B. The role of inflammation in the pathogenesis of prostate cancer. J Urol 2004;172(5):6–11.
7. Palapattu G.S., Sutcliffe S., Bastian P.J. et al. Prostate carcinogenesis and inflammation: emerging insights. Carcinogenesis 2005;26(7):1170–81.
8. De Marzo A.M., Platz E.A., Sutcliffe S. et al. Inflammation in prostate carcinogenesis. Nat Rev Cancer 2007;7(4):256–69.
9. Male lower urinary tract symptoms. Evaluation and management. 6th International Consultation on Prostate Cancer and Prostatic Diseases. McConnell J., Abrams P., Denis L., Khoury S., Roehrborn C.G., eds. Paris, France: Health Publications, 2006. 401 p.
10. Lee S.E., Ku J.H., Park H.K. et al. Prostatic calculi do not influence the level of serum prostate specific antigen in men without clinically detectable prostate cancer or prostatitis. J Urol 2003;170(3):745−8.
11. Hwang E.C., Choi H.S., Im C.M. et al. Prostate calculi in cancer and BPH in a cohort of Korean men: Presence of calculi did not correlate with cancer. Asian J Andrology 2010;12(2):215−20.
Review
For citations:
Guseinov F.I., Vinarov A.Z. ВЗАИМОСВЯЗЬ ПРОСТАТИЧЕСКИХ КАМНЕЙ И РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ. Cancer Urology. 2012;8(3):72-75. (In Russ.) https://doi.org/10.17650/1726-9776-2012-8-3-72-75