SOME SPECIFIC FEATURES OF THE DIAGNOSIS AND TREATMENT OF KIDNEY CANCER IN RUSSIA: PRELIMINARY RESULTS OF A MULTICENTER COOPERATIVE STUDY

An interim analysis of the database comprising information on 7813 kidney cancer (KC) patients who had been treated or followed up in 25 health care facilities of Russia yielded some patient characteristics, the specific features of the tumor process, and main approaches to surgical and medical treatments. Such characteristics as a male-to-female patient ratio, stage distribution in patients, detection rate of different histological types of KC and different tumor grades, proportion of organ-saving and organ-removing interventions, drug treatments for metastatic KC are considered.

kidney cancer, clinical and pathomorphological stages, histological types, tumor differentiation, overall survival, relapse-free survival

1. Parkin D.M., Bray F., Ferlay J., Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74–108.

2. Keane T., Gillatt D., Evans C.P., Tubaro A. Current and future trends in treatment of renal cancer. Eur Urol 2007;Suppl 6:374−84.

3. Ferlay F., Autier P., Boniol M. et al. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 2007;18:581−92.

4. Злокачественные новообразования в России в 2010 году. Под ред. В.И. Чиссова, В.В. Старинского, Г.В. Петровой. М., 2011.

5. Chow W.H., Dong L.M., Devesa S.S. Epidemiology and risk factors for kidney cancer. Nat Rev Urol 2010;7(5):245−57.

6. Edwards B.K., Howe H.L., Ries L.A. et al. Annual report to the nation on the status of cancer, 1973−1999, featuring implications of age and aging on U.S. cancer burden. Cancer 2002;94(10):2766−92.

7. Lee C.T., Katz J., Fearn P.A., Russo P. Mode of presentation of renal cell carcinoma provides prognostic information. Urol Oncol 2002;7(4):135−40.

8. Patard J.J., Leray E., Cindolo L. et al. Multi-institutional validation of a symptom based classification for renal cell carcinoma. J Urol 2004;172(3):858−62.

9. Kane C.J., Mallin K., Ritchey J. et al. Renal cell cancer stage migration: analysis of the National Cancer Data Base. Cancer 2008;113(1):78−83.

10. Eble J.N., Sauter G., Epstein J.I., Sesterhenn I.A. (eds). In: Pathology and genetics of tumors of the urinary system and male genital organs. World Health Organization Classification of Tumors. Lyons: IARC Press, 2004; p. 7.

11. Baillargeon-Gagné S., Jeldres C., Lughezzani G. et al. A comparative population-based analysis of the rate of partial vs radical nephrectomy for clinically localized renal cell carcinoma. BJU Int 2010; 105(3):359−64.

12. Kümmerlin I.P., ten Kate F.J., Wijkstra H.J. A decade of surgically removed small renal masses in the Netherlands: characteristics and trends in type of surgery and pathologic reporting. Endourol 2010; 24(10):1675−9.

13. Ljungberg B., Cowan N., Hanbury D.C., Hora M. et al. Guidelines on renal cell carcinoma. European Association of Urology Web site. http://www.uroweb.org/guidelines/online-guidelines/.

14. National Comprehensive Cancer Network, Cancer — and Treatment — Kidney Cancer, Practice Guidelines in Oncology — v.1.2012.