NEPHROBLASTOMATOSIS IN CHILDREN: REVIEW OF LITERATURE AND THE AUTHORS’ STUDY FINDINGS
https://doi.org/10.17650/1726-9776-2009-5-4-19-24
Abstract
Some nontumor processes can resemble renal tumors both clinically and morphologically. Malformations in the kidneys can lead to that the latter preserve primitive renal tissue elements that can be mistaken for nephroblastic tumors. In their clinical practice, pediatric oncologists most frequently come across, among the tumor-like processes simulating nephroblastoma (NB), a massive renal blastema that is also known as nephroblastomatosis (NBM). The paper demonstrates that there is no unified notion of NBM in children and that of a need and options for treatment. It presents data on 37 patients with bilateral NB, the development of which NBM is responsible for. The morphological and radiological signs of NBM are given. The results of treatment in the patients are provided in relation to the extent of a tumor process and the concomitance of NBM and Wilms’ tumor. NBM is shown to be a self-limiting pretumor proliferative process that is characterized by a high NB risk. When the diagnosis of NBM is verified, the patient needs antitumor treatment.
About the Authors
T. A. Sharoyev
Research-Practical Center for Medical Care to Children, Health Care Department, Moscow
Russian Federation
Russian Federation
I. N. Sokolova
Research Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Russian Federation
N. M. Ivanova
Research Institute of Pediatric Oncology and Hematology
Russian Federation
Russian Federation
M. V. Rubanskaya
Research Institute of Pediatric Oncology and Hematology
Russian Federation
Russian Federation
N. A. Koshechkina
Research Institute of Pediatric Oncology and Hematology
Russian Federation
Russian Federation
T. R. Panferova
Research Institute of Pediatric Oncology and Hematology
Russian Federation
Russian Federation
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Review
For citations:
Sharoyev T.A., Sokolova I.N., Ivanova N.M., Rubanskaya M.V., Koshechkina N.A., Panferova T.R. NEPHROBLASTOMATOSIS IN CHILDREN: REVIEW OF LITERATURE AND THE AUTHORS’ STUDY FINDINGS. Cancer Urology. 2009;5(4):19-24. (In Russ.) https://doi.org/10.17650/1726-9776-2009-5-4-19-24
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