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DIAGNOSTIC VALUE OF ANGIOGENESIS RATES IN RENAL-CELL CARCINOMA

https://doi.org/10.17650/1726-9776-2011-7-3-25-30

Abstract

The results of research in 130 patients with space-occupying lesions of kidneys treated in MCH n.a. S.R. Mirotvorcev were analysed. The diagnostic significance of metabolic tumor marker TuM2Pk, matrix metalloproteinases ММР-9, ММP-3, vascular endothelial growth factor (VEGF) and angiogenic cytokines (TNF-α, IL-8, IL-12) was evaluated. It was determined that VEGF detection in blood serum has the most important diagnostic value in differential diagnosis between renal tumor and renal cyst and in TNM staging.

About the Authors

P. V. Glybochko
I.M. Sechenov First Moscow Medical University
Russian Federation


N. B. Zacharova
State Medical Univercity n.a. V.I. Razumovskiy
Russian Federation


A. N. Ponukalin
State Medical Univercity n.a. V.I. Razumovskiy
Russian Federation


D. A. Durnov
State Medical Univercity n.a. V.I. Razumovskiy
Russian Federation


N. K. Shachpazyan
State Medical Univercity n.a. V.I. Razumovskiy
Russian Federation


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Review

For citations:


Glybochko P.V., Zacharova N.B., Ponukalin A.N., Durnov D.A., Shachpazyan N.K. DIAGNOSTIC VALUE OF ANGIOGENESIS RATES IN RENAL-CELL CARCINOMA. Cancer Urology. 2011;7(3):25-30. (In Russ.) https://doi.org/10.17650/1726-9776-2011-7-3-25-30

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