HIGH-RISK PROSTATE CANCER: THE ONCOLOGICAL EFFICIENCY OF RADICAL PROSTATECTOMY
https://doi.org/10.17650/1726-9776-2014-10-1-53-57
Abstract
Patients with high-risk prostate cancer (PC) make up a heterogeneous population who has a substantially varying benefit from surgical treatment. The long-term oncological results of radical prostatectomy (RPE) were studied in 446 high D’Amico-risk PC patients. Overall 5- and 10-year relapse-free survival (RFS) rates were 65 and 62 %; overall 10- and 15-year cancer-specific survival (CSS) rates were 92.6 and 82.6 %. Patients with the completely removed tumor located in the histologic specimen (HS) benefited most greatly from RPE. In the HS located and unlocated tumor groups, 5-year RFS rates were 79.6 and 32.7 %; 10-year CSS rates were equal to 100 and 78.6 %. The number of preoperative high risk factors had a significant impact on outcomes. In the 1, 2, and 3 risk factor groups, 5-year RFS rates were 76.7, 39, and 35.3 % and 10-year CSS rates were equal to 97.8, 85.4, and 64.2 %, respectively.
About the Authors
E. I. Veliyev
Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow
Russian Federation
Russian Federation
E. A. Sokolov
Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow
Russian Federation
Russian Federation
O. B. Loran
Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow
Russian Federation
Russian Federation
S. B. Petrov
A. M. Nikiforov All-Russian Center of Emergency and Radiation Medicine, Ministry of Emergency Situations of Russia, Saint Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Veliyev E.I., Sokolov E.A., Loran O.B., Petrov S.B. HIGH-RISK PROSTATE CANCER: THE ONCOLOGICAL EFFICIENCY OF RADICAL PROSTATECTOMY. Cancer Urology. 2014;10(1):53-57. (In Russ.) https://doi.org/10.17650/1726-9776-2014-10-1-53-57
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