PROGNOSTIC FACTORS OF PROSTATE CANCER SYSTEMIC PROGRESSION IN PATIENTS WITH BIOCHEMICAL RECURRENCE AFTER RADICAL PROSTATECTOMY
https://doi.org/10.17650/1726-9776-2013-9-1-62-67
Abstract
The impact of different prognostics factors on the probability of development local and systemic relups in patient with biochemical recurrence following prostatectomy was studied. By multivariable analysis, predictors of systemic progression were seminal vesicle invasion (pT3b) (p = 0,005), trigger prostate-specific antigen level greater than 2 ng/mL (p = 0,03), prostate-specific antigen doubling time of 6 months or less (p = 0,002) and prostate-specific antigen velocity greater than 0,1 ng/mL per month (p < 0,0001). The rate of systemic progression in patient with not greater than one unfavorable predictor was 6,3 %, with two or greater predictors – 88,9 % (p < 0,001).
About the Authors
P. D. Demeshko
N.N. Alexandrov National Cancer Center of Belarus, Minsk
Belarus
Belarus
S. A. Krasny
N.N. Alexandrov National Cancer Center of Belarus, Minsk
Belarus
Belarus
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Review
For citations:
Demeshko P.D., Krasny S.A. PROGNOSTIC FACTORS OF PROSTATE CANCER SYSTEMIC PROGRESSION IN PATIENTS WITH BIOCHEMICAL RECURRENCE AFTER RADICAL PROSTATECTOMY. Cancer Urology. 2013;9(1):62-67. (In Russ.) https://doi.org/10.17650/1726-9776-2013-9-1-62-67
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