Robot-assisted radical cystectomy with intracorporeal orthotopic cystoplasty
https://doi.org/10.17650/1726-9776-2019-15-4-100-107
Abstract
Background. Radical cystectomy uses laparoscopic and robotic approaches along with the open ones.
Objective: to study immediate results of robot-assisted radical cystectomy with intracorporeal orthotopic cystoplasty.
Materials and methods. Robot-assisted radical cystectomy with intracorporeal orthotopic cystoplasty was performed in 15 patients (13 male, 2 female), aged 64–76 years. Fourteen patients had bladder cancer, 1 female – a postradiation bladder fistula and microcystis. T2 stage was detected in 8 (57.1 %) patients, T3 – in 6 (42.9 %). After the operation we evaluated operation time, blood loss volume, hospital stay, functional and oncological results.
Results. Average operation time was 380 (320–560) minutes, blood loss volume – 80–200 ml, blood transfusion was not performed. Early complications (up to 30 days) were observed in 7 patients (46.7 %), late ones (90‑days) – in 6 (40.0 %). There were no cases of intestinal obstruction. Patients with ureteral-intestinal (n = 2) and reservoir-urethral (n = 1) anastomosis failure underwent percutaneous renal drainage. One patient died of acute myocardial infarction. Daytime continence was 80.0 %, nocturnal – 53.3 %. One patient died of disease progression within 7.6 observation months.
Conclusion. Robot-assisted radical cystectomy with intracorporeal urine diversion is a modern and minimally invasive method for patients with muscle-invasive bladder cancer. More experience in this field will allow to reduce surgery time and number of complications.
About the Authors
B. G. GulievRussian Federation
Department of Urology, I. I. Mechnikov North-West State Medical University, Ministry of Health of Russia
41 Kirochnaya St., Saint-Petersburg 191015,
56 Liteynyy Prospekt, Saint-Petersburg 191014
B. K. Komyakov
Department of Urology
41 Kirochnaya St., Saint-Petersburg 191015
R. R. Bolokotov
56 Liteynyy Prospekt, Saint-Petersburg 191014
References
1. Stenzl A., Cowan N.C., Santis M. et al. The updated EAU guidelines on muscleinvasive and metastatic bladder cancer. Eur Urol 2009;55(4):815–25. DOI: 10.1016/j.eururo.2009.01.002.
2. Hautmann R.E., de Petriconi R.C., Pfeiffer C. et al. Radical cystectomy for urothelial carcinoma of the bladder without neoadjuvant or adjuvant therapy: longterm results in 1100 patients. Eur Urol 2012;61:1039–47. DOI: 10.1016/j.eururo.2012.02.028.
3. Gakis G., Efstathiou J., Lerner S.P. et al. ICUD-EAU International Consultation on Bladder Cancer 2012: radical cystectomy and bladder preservation for muscle-invasive urothelial carcinoma of the bladder. Eur Urol 2013;63(1):45–57. DOI: 10.1016/j.eururo.2012.08.009.
4. Kiss B., Burkhad F.C., Thalmann G.N. Open radical cystectomy: still the gold standard for muscle invasive bladder cancer. World J Urol 2016;34(1):33–9. DOI: 10.1007/s00345-015-1729-7.
5. Shabsigh A., Korets R., Vera K.C. et al. Defining early morbidity of radical cystectomy for patients with bladder cancer using a standardized reporting methodology. Eur Urol 2009;55:164–74. DOI: 10.1016/j.eururo.2008.07.031.
6. Kauffman E.C., Ng C.K., Lee M.M. et al. Early oncological outcomes for bladder urothelial carcinoma patients treated with robotic radical cystectomy. BJU Int 2011;107:628–35. DOI: 10.1111/j.1464-410X.2010.09577.
7. Albisinni S., Oderda M., Fossion L. et al. The morbidity of laparoscopic radical cystectomy: analysis of postoperative complications in a multicenter cohort by the European Association of Urology Section of Uro-Technology. World J Urol 2016;34:149–56. DOI: 10.1007/s00345015-1633-1.
8. Pruthi R.S., Nix J., McRackan D. et al. Robotic-assisted laparoscopic intracorporeal urinary diversion. Eur Urol 2010;57:1013– 21. DOI: 10.1016/j.eururo.2009.12.028.
9. Collins J.W., Tyritzis S., Nyberg T. et al. Robot-assisted radical cystectomy: description of an evolved approach to radical cystectomy. Eur Urol 2013;64:654–63. DOI: 10.1016/j.eururo.2013.05.020.
10. Desai M.M., Gill I.S., de Castro Abreu A.L. et al. Robotic intracorporeal orthotopic neobladder during radical cystectomy in 132 patients. J Urol 2014;192:1734–40. DOI: 10.1016/j.juro.2014.06.087.
11. Beecken W.D., Wolfram M., Engl T. et al. Robotic-assisted laparoscopic radical cystectomy and intra-abdominal formation of an orthotopic ileal neobladder. Eur Urol 2003;44:337–9.
12. Hu J.C., Chugtai B., O’Malley P. et al. Perioperative outcomes, health care costs and survival after robotic-assisted versus open radical cystectomy: a national comparative effectiveness study. Eur Urol 2016;70:195–202. DOI: 10.1016/j.eururo.2016.03.028.
13. Knox M.L., El-Galley R., Busby J.E. Robotic versus open radical cystectomy: identification of patients who benefit from the robotic approach. J Endourol 2013;27:40–4. DOI: 10.1089/end.2012.0168.
14. Bochner B.H., Dalbagni G., Marzouk K.H. et al. Randomized trial comparing open radical cystectomy and robotassisted laparoscopic radical cystectomy: oncologic results. Eur Urol 2018;74:465– 71. DOI: 10.1016/j.eururo.2018.04.030.
15. Sathianathen N.J., Kalapara A., Frydenberg M. et al. Robotic assisted radical cystectomy vs open radial cystectomy: systematic review and meta-analysis. J Urol 2019; 201:715–20. DOI: 10.1016/j.juro.2018.10.006.
16. Jonsson M.N., Adding L.C., Hosseini A. et al. Robot-assisted radical cystectomy with intracorporeal urinary diversion in patients with transitional cell carcinoma of the bladder. Eur Urol 2011;60:1066–73. DOI: 10.1016/j.eururo.2011.07.035.
17. Ahmed K., Khan S.A., Hyan M.H. et al. Analysis of intracorporeal compared with extracorporeal urinary diversion after robotassisted radical cystectomy results from the International Robotic Cystectomy Consortium. Eur Urol 2014;65:340–7. DOI: 10.1016/j.eururo.2013.09.042.
18. Hussein A.A., May P.R., Jing Zh. et al. Outcomes of intracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. J Urol 2018;199: 1302–11. DOI: 10.1016/j.juro.2017.12.045.
19. Wiklund N.P., Poulakis V. Robotic neobladder. BJU Int 2011;107:1514–37. DOI: 10.1111/j.1464-410X.2011.10307x.
20. Chopra S., de Castro Abreu A.L., Berger A.K. et al. Evolution of robot-assisted orthotopic ileal neobladder formation: a stepbystep update to the University of Southern California techniques. BJU Int 2017;119:185–91. DOI: 10.1111/bju.13611.
21. Sim Al., Todenhofer T., Mischinger J. et al. Y-pouch neoblader – a simplified method of intracorporeal neobladder after robotic cystectomy. J Endourol 2015;29(4):387–9. DOI: 10.1089/end.2014.0507.
22. Hussein A.A., Ahmed Y.E., Kozlowski J.D. et al. Robot-assisted approach to “W”-configuration urinary diversion: step-by-step technique. BJU Int 2017;120:152–7. DOI: 10.1111/bju.13824.
23. Simone G., Papalia R., Misuraca L. et al. Robotic intracorporeal padua ileal bladder: surgical technique, perioperative, oncologic and functional outcomes. Eur Urol 2018;73:934–40. DOI: 10.1016/j.eururo.2016.10.018.
24. Guliev B.G., Komyakov B.K., Bolotokov R.R., Il’in D.M. Robot-assisted radical cystectomy (initial experience). Urology Herald 2018;4:13–20. (In Russ.). DOI: 10.21886/2308-6424-2018-6-4-13-20.
25. Zakaria A.S., Santos F., Dragomir A. et al. Postoperative mortality and complications after radical cystectomy for bladder cancer in Quebec: a population-based analysis during the years 2000–2009. Can Urol Assoc J 2014;8:259–67. DOI: 10.5489/cuaj.1997.
26. Lenfant L., Verhoest G., Campi R. et al. Perioperative outcomes and complications of intracorporeal vs extracorporeal urinary diversion after robot-assisted radical cystectomy for bladder cancer: a real-life, multi-institutional french study. World J Urol 2018;36(11): 1711–8. DOI: 10.1007/s00345-018-2313-8.
Review
For citations:
Guliev B.G., Komyakov B.K., Bolokotov R.R. Robot-assisted radical cystectomy with intracorporeal orthotopic cystoplasty. Cancer Urology. 2019;15(4):100-107. (In Russ.) https://doi.org/10.17650/1726-9776-2019-15-4-100-107