Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm
Yu. I. Osmanov,
E. A. Kogan,
L. O. Severgina,
L. M. Rapoport,
N. S. Aleksandrov,
D. G. Tsarichenko,
D. O. Korolyov https://doi.org/10.17650/1726-9776-2019-15-3-126-131
Abstract
In the structure of oncological morbidity, renal cell carcinoma takes the 10th place among malignant neoplasms. The increase in incidence is observed from the age of 35–40 years and reaches a maximum at the age of 65–70 years. In terms of frequency of occurrence, clear cell renal cell carcinoma is ranked first among all kidney tumors. Meanwhile, due to the high heterogeneity of renal cell carcinomas with clear cytoplasm group, significant differential diagnostic difficulties arise in the morphological verification of these tumors. The article presents all nosological forms of kidney tumors with clear cytoplasm and provides a database of already known immunohistochemical markers for each nosological unit.
About the Authors
Yu. I. Osmanov
Sechenov First Moscow State Medical University, Ministry of Health of Russia;
Scientific Clinical Center, Russian Railway
Russian Federation
Russian Federation
Anatomic Pathology Department Sechenov First Moscow State Medical University, Ministry of Health of Russia;
Department of Pathology Scientific Clinical Center, Russian Railway
Build. 2, 8 Trubetskaya St., Moscow 119991,
84 Volokolamskoe Shosse, Moscow 125367
E. A. Kogan
Sechenov First Moscow State Medical University, Ministry of Health of Russia
Anatomic Pathology Department
Build. 2, 8 Trubetskaya St., Moscow 119991
L. O. Severgina
Sechenov First Moscow State Medical University, Ministry of Health of Russia
Anatomic Pathology Department
Build. 2, 8 Trubetskaya St., Moscow 119991
L. M. Rapoport
Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Ministry of Health of Russia
84 Volokolamskoe Shosse, Moscow 125367
N. S. Aleksandrov
Sechenov First Moscow State Medical University, Ministry of Health of Russia
Anatomic Pathology Department
Build. 2, 8 Trubetskaya St., Moscow 119991
D. G. Tsarichenko
Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Ministry of Health of Russia
84 Volokolamskoe Shosse, Moscow 125367
D. O. Korolyov
Institute for Urology and Reproductive Health, Sechenov First Moscow State Medical University, Ministry of Health of Russia
84 Volokolamskoe Shosse, Moscow 125367
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Review
For citations:
Osmanov Yu.I., Kogan E.A., Severgina L.O., Rapoport L.M., Aleksandrov N.S., Tsarichenko D.G., Korolyov D.O. Clinical and morphological features, immune profile of renal cell tumors with clear cytoplasm. Cancer Urology. 2019;15(3):126-131. (In Russ.) https://doi.org/10.17650/1726-9776-2019-15-3-126-131
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