Expression of platelet-derived growth factor alpha and beta genes PDGFRA and PDGFRB associated with biochemical recurrence of prostate cancer after radical prostatectomy
https://doi.org/10.17650/1726-9776-2017-13-4-45-50
Abstract
We performed genome-wide transcriptome meta-analysis of prostate cancer samples after radical prostatectomy of patients without lymph node metastasis. Significant associations were determined between expression of platelet-derived growth factor alpha and beta genes (PDGFRA and PDGFRB) and probability and time of onset of biochemical recurrence.
About the Authors
M. Yu. Shkurnikov
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinskiy Proezd, Moscow 125284
Russian Federation
3 2nd Botkinskiy Proezd, Moscow 125284
B. Ya. Alekseev
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinskiy Proezd, Moscow 125284
Russian Federation
3 2nd Botkinskiy Proezd, Moscow 125284
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Review
For citations:
Shkurnikov M.Yu., Alekseev B.Ya. Expression of platelet-derived growth factor alpha and beta genes PDGFRA and PDGFRB associated with biochemical recurrence of prostate cancer after radical prostatectomy. Cancer Urology. 2017;13(4):45-50. https://doi.org/10.17650/1726-9776-2017-13-4-45-50
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