NONINVASIVE DIAGNOSIS OF URINARY BLADDER CANCER BY CROSS-POLARIZATION OPTICAL COHERENCE TOMOGRAPHY: CLINICAL RESULTS
https://doi.org/10.17650/1726-9776-2010-6-3-25-31
Abstract
The investigation examined the feasibility of cross-polarization optical cohe-rence tomography (CP OCT) to detect early urinary bladder cancer (UBC). Studies were performed in 376 patients; 5290 images were obtained using an OCT 133-U optical coherence tomograph. To acquire and compare intrared-light scattering images in baseline and orthogonal polarizations is the basis of CP OCT; their analysis makes it possible to judge from the state of the epithelium/connective tissue system and to obtain information on changes in tissue depolarizing components, collagen in particular. The authors elaborated criteria as determinants of the nature of CP OCT changes in direct and orthogonal polarizations in health, inflammatory changes, and UBC at its early stage - urothelial dysplasia and carcinoma in situ in flat suspected areas.
About the Authors
O. S. Streltsova
Department of Urology
Russian Federation
Russian Federation
N. D. Gladkova
Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy
Russian Federation
Russian Federation
E. B. Kiseleva
Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy
Russian Federation
Russian Federation
M. M. Karabut
Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy
Russian Federation
Russian Federation
E. A. Tararova
Department of Urology
Russian Federation
Russian Federation
K. E. Yunusova
Department of Morbid Anatomy
Russian Federation
Russian Federation
V. N. Krupin
Department of Urology
Russian Federation
Russian Federation
E. V. Zagainova
Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy
Russian Federation
Russian Federation
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Review
For citations:
Streltsova O.S., Gladkova N.D., Kiseleva E.B., Karabut M.M., Tararova E.A., Yunusova K.E., Krupin V.N., Zagainova E.V. NONINVASIVE DIAGNOSIS OF URINARY BLADDER CANCER BY CROSS-POLARIZATION OPTICAL COHERENCE TOMOGRAPHY: CLINICAL RESULTS. Cancer Urology. 2010;6(3):25-31. (In Russ.) https://doi.org/10.17650/1726-9776-2010-6-3-25-31
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