DIAGNOSTICS AND TREATMENT OF TUMORS OF A TESTICLE AT CHILDREN: 19 YEARS OF EXPERIENCE
https://doi.org/10.17650/1726-9776-2014-10-1-64-68
Abstract
From 1990 to 2009, at the Research Institute for OBCs were examined and treated 62 children with testicular germ cell tumors. The average age of our patients was 3.7 years (range 3 months to 15 years). All children performed a study of tumor markers titer, ultrasound. In 14 children identified metastases. Surgical treatment is the first stage in the volume orhifunikulektomii conducted all 62 children. Retroperitoneal limfoadenektomiya made in 4 children and 5 children underwent thoracotomy with removal of metastases in the lung. Drug treatment was performed in 47 children with malignant germ cell tumor. Using a combined method in the treatment of malignant testicular tumors led to 100 % relapse-free and overall survival.
About the Authors
M. A. RokhoevRussian Federation
I. V. Nechushkina
Russian Federation
E. V. Mikhaylova
Russian Federation
P. A. Kerimov
Russian Federation
O. A. Kapkova
Russian Federation
References
1. Alanee S., Shukla A. Paediatric testicular cancer: an updated review of incidence and conditional survival from the Surveillance, Epidemiology and End Results database. BJU Int 2009;104:1280–83.
2. Kusumakumary P., Mathew B. S., Hariharan S. et al. Testicular germ cell tumors in prepubertal children. Pediatr Hematol Oncol 2000;17(1):105–11.
3. Richie J. P., Steele G. S. Neoplasms of the testis. In: A. J. Wein, L. R. Kavoussi, A. C. Novick, A. W. Partin, C. A. Peters, editors. Campbell Walsh Urology. Philadelphia: Saunders 2007; 893–935.
4. Kramer S. A., Kelalis P. P. Testicular tumors in children. In: N. Javadpour, ed. Principles and Management of Testicular Cancer. New York: Thieme, 1986.
5. WHO histological classification of testis tumours, In: J. N. Eble, G. Sauter, J. I. Epstein, I. A. Sesterhenn, eds. Pathology & Genetics. Tumours of the urinary system and male genital organs. Lyons: IARC Press, 2004: 218, pp. 250–262.
6. Wu H., Snyder H. M. 3rd. Pediatric urologic oncology: bladder, prostate, testis. Urol Clin North Am 2004;31:619.
7. Oottamasathien S., Thomas J. C., Adams M. C. et al. Testicular tumours in children: a singleinstitutional experience. BJU Int 2007;99(5):1123–6.
8. Miki T., Mizutani Y., Akaza H. et al. Long-term results of first-line sequential high-dose carboplatin, etoposide and ifosphamide chemotherapy with peripheral blood stem cell support for patients with advanced testicular germ cell tumor. Int J Urol 2007;14:54–9.
9. Ross J. H., Rybicki L., Kay R. Clinical behavior and a contemporary management algorithm for prepubertal testis tumors: a summary of the Prepubertal Testis Tumor Registry. J Urol 2002; 168:1675.
Review
For citations:
Rokhoev M.A., Nechushkina I.V., Mikhaylova E.V., Kerimov P.A., Kapkova O.A. DIAGNOSTICS AND TREATMENT OF TUMORS OF A TESTICLE AT CHILDREN: 19 YEARS OF EXPERIENCE. Cancer Urology. 2014;10(1):64-68. (In Russ.) https://doi.org/10.17650/1726-9776-2014-10-1-64-68