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Metanephric adenoma of the kidney: clinical case and literature review

https://doi.org/10.17650/1726-9776-2023-19-3-119-125

Abstract

Metanephric adenoma is a rare benign kidney tumor with a favorable prognosis. These neoplasms are often interpreted as malignant at the preoperative stage, since they do not have specific characteristics showing during instrumental imaging methods, which leads to excessive surgical treatment in the context of nephrectomy volume. Therefore, histological verification is the gold standard for diagnosis. The morphological features of metanephric adenoma are in many ways similar to such kidney tumors as papillary renal cell carcinoma and nephroblastoma (Wilms’ tumor), so sometimes additional research methods are required, including immunohistochemical and molecular genetic ones. In this article, we report a rare clinical case of metanephric adenoma in a forty-seven-year-old woman. The results of clinical and instrumental exams, as well as morphological features of the tumor are presented. A review  of the literature on the clinical, morphological, and molecular aspects of this tumor is also presented.

About the Authors

E. V. Grebenkin
UNIM; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Russian Federation

Evgeniy V. Grebenkin.

Build. 6, 26 Podsosenskiy Pereulok, Moscow 101000; 31 Kashirskoe Shosse, Moscow 115409


Competing Interests:

None



A. M. Pshikhachev
K+31 Clinic; M.V. Lomonosov Moscow State University
Russian Federation

Build. 4, 42 Lobachevskogo St., Moscow 119415; Build. 1, 27 Lomonosovskiy Prospekt, Moscow 119192


Competing Interests:

None



B. E. Osmolovskiy
K+31 Clinic
Russian Federation

Build. 4, 42 Lobachevskogo St., Moscow 119415


Competing Interests:

None



A. A. Epishkina
UNIM; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Russian Federation

Build. 6, 26 Podsosenskiy Pereulok, Moscow 101000; 31 Kashirskoe Shosse, Moscow 115409


Competing Interests:

None



E. Yu. Kozhevnikova
UNIM
Russian Federation

Build. 6, 26 Podsosenskiy Pereulok, Moscow 101000


Competing Interests:

None



N. I. Sorokin
M.V. Lomonosov Moscow State University
Russian Federation

Build. 1, 27 Lomonosovskiy Prospekt, Moscow 119192


Competing Interests:

None



A. A. Kamalov
K+31 Clinic; M.V. Lomonosov Moscow State University
Russian Federation

Build. 4, 42 Lobachevskogo St., Moscow 119415; Build. 1, 27 Lomonosovskiy Prospekt, Moscow 119192


Competing Interests:

None



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Review

For citations:


Grebenkin E.V., Pshikhachev A.M., Osmolovskiy B.E., Epishkina A.A., Kozhevnikova E.Yu., Sorokin N.I., Kamalov A.A. Metanephric adenoma of the kidney: clinical case and literature review. Cancer Urology. 2023;19(3):119-125. (In Russ.) https://doi.org/10.17650/1726-9776-2023-19-3-119-125

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ISSN 1726-9776 (Print)
ISSN 1996-1812 (Online)
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