Carcinosarcoma of the prostate: clinical observation and literature review
https://doi.org/10.17650/1726-9776-2023-19-3-113-118
Abstract
Carcinosarcoma is a rare type of prostate neoplasms and accounts for less than 1 % of all malignant tumors of the prostate. This kind of tumor is characterized by the absence of prostate-specific antigen elevation in most cases, which leads to diagnosis of metastatic disease in a quarter of patients. Moreover, carcinosarcoma of the prostate has an extremely poor clinical prognosis. From the morphological point of a view, biphasicity is a typical feature for these tumors. As a rule, epithelial component is represented by poorly differentiated acinar adenocarcinoma. However, in some literature cases adenogenous component was represented by ductal or neuroendocrine carcinoma. Sarcoma component can be represented by any sarcoma type. Currently, pathogenesis of carcinosarcomas isn’t clear. In this report, we describe a clinical case of carcinosarcoma of the prostate in a 72-year-old male.
About the Authors
V. S. Surkova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Competing Interests:
Russian Federation
Viktoriya S. Surkova.
3 2nd Botkinskiy Proezd, Moscow 125284
Competing Interests:
None
N. N. Volchenko
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Competing Interests:
Russian Federation
Nadezhda N. Volchenko.
3 2nd Botkinskiy Proezd, Moscow 125284
Competing Interests:
None
A. M. Lavrova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Competing Interests:
Russian Federation
Anastasiia M. Lavrova.
3 2nd Botkinskiy Proezd, Moscow 125284
Competing Interests:
None
Kh. S. Kosumova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Competing Interests:
Russian Federation
Khadizhat S. Kosumova.
3 2nd Botkinskiy Proezd, Moscow 125284
Competing Interests:
None
G. G. Khakimova
Tashkent City Branch of the Republican Specialized Scientific Practical Medical Center of Oncology and Radiology; Department of Oncology, Children’s Oncology, Tashkent Pediatric Medical Institute
Uzbekistan
Competing Interests:
Uzbekistan
Gulnoz G. Khakimova.
1 Bagistan St., Tashkent 100070; 223 Bogishamol St., Tashkent 100140
Competing Interests:
None
M. V. Grebenkin
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Competing Interests:
Russian Federation
Maxim V. Grebenkin.
Build. 1, 51 3rd Parkovaya St., Moscow 105425
Competing Interests:
None
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Review
For citations:
Surkova V.S., Volchenko N.N., Lavrova A.M., Kosumova Kh.S., Khakimova G.G., Grebenkin M.V. Carcinosarcoma of the prostate: clinical observation and literature review. Cancer Urology. 2023;19(3):113-118. (In Russ.) https://doi.org/10.17650/1726-9776-2023-19-3-113-118
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