PROGNOSTIC FACTORS OF PROSTATE CANCER BEFORE AND AFTER RADICAL PROSTATECTOMY
https://doi.org/10.17650/1726-9776-2011-7-2-52-53
Abstract
Objective: to assess a correlation between the preoperative prognostic characteristics and the pathologic stage and to determine whether a positive surgical margin is present after radical prostatectomy (RPE).
Materials and methods. The materials of 224 patients with prostate cancer (PC) who had undergone RPE at the Clinic of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, were analyzed.
Results. The patients’ median age was 62 (43–78) years. Sixty-seven (29.9 %), 46 (20.5%), and 111 (49.6 %) patients were referred to as low-, moderate-, and high-risk groups, respectively. A positive surgical margin was observed in 11.9, 28.3, and 38.7 % of the patients in the low-, moderate-, and high-risk groups, respectively (р = 0.0003). The predictors of a positive surgical margin were the percent of involved biopsy specimens (R = 0.34) and Gleason score (R = 0.31) and perineural invasion. According to multivariate analysis, neither the preoperative level of prostate-specific antigen, nor the clinical stage showed any correlation with the positive surgical margin and the pathologic stage after RPE.
About the Authors
E. I. Veliev
Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow
Russian Federation
Russian Federation
V. E. Okhrits
Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow
Russian Federation
Russian Federation
A. Kh. Obeid
Department of Urology and Surgical Andrology, Russian Medical Academy of Postgraduate Education, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Veliev E.I., Okhrits V.E., Obeid A.Kh. PROGNOSTIC FACTORS OF PROSTATE CANCER BEFORE AND AFTER RADICAL PROSTATECTOMY. Cancer Urology. 2011;7(2):52-53. (In Russ.) https://doi.org/10.17650/1726-9776-2011-7-2-52-53
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