Bladder leiomyosarcoma originating from the muscular elements of the bladder mucosa (clinical case)
I. A. Reva,
K. M. Nyushko,
E. N. Plekhanova,
V. D. Sanikovich,
A. S. Chernushenko,
N. D. Akhvlediani,
D. Yu. Pushkar https://doi.org/10.17650/1726-9776-2022-18-1-106-111
Abstract
Leiomyosarcoma of the bladder is an extremely aggressive malignant tumor. Today in the world literature there are a little more than 200 described cases of bladder leiomyosarcoma. In all the cases described, the neoplasm originated from the proper muscle layer of the bladder. In this work, we present a unique clinical case – bladder leiomyosarcoma originating from the muscular elements of the bladder mucosa.
About the Authors
I. A. Reva
Clinical Medical Center, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
Igor A. Reva
1А Kuskovskaya St., Moscow 111398
K. M. Nyushko
Clinical Medical Center, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia;
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
1А Kuskovskaya St., Moscow 111398,
3 2nd Botkinskiy Proezd, Moscow 125284
E. N. Plekhanova
Clinical Medical Center, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
1А Kuskovskaya St., Moscow 111398
V. D. Sanikovich
Clinical Medical Center, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia;
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Oncology and Radiation Therapy A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
1А Kuskovskaya St., Moscow 111398,
2 Budayskaya St., Moscow 129128
A. S. Chernushenko
Clinical Medical Center, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
1А Kuskovskaya St., Moscow 111398
N. D. Akhvlediani
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology
21 Vucheticha St., Moscow 125206
D. Yu. Pushkar
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology
21 Vucheticha St., Moscow 125206
References
1. Labanaris A.P., Zugor V., Meyer B. et al. Urinary bladder leiomyosarcoma in adults. Int Urol Nephrol 2008;40(2):311–6. DOI: 10.1007/s11255-007-9288-5.
2. Menon A.R., Puthalath R.T., Suresh N., Hegde S. Organ preservation in leiomyosarcoma bladder: case report and review of literature. Urol Ann 2018;10(2):233–6. DOI: 10.4103/UA.UA_109_17.
3. Baurys W., Landes R.R. Leiomyosarcoma of the bladder; report of a case. Guthrie Clin Bull 1946;15:127–32.
4. Zieschang H., Koch R., Wirth M.P., Froehner M. Leiomyosarcoma of the urinary bladder in adult patients: a systematic review of the literature and meta-analysis. Urol Int 2019;102(1):96–101. DOI: 10.1159/000494357.
5. Coiner B.L., Cates J., Kamanda S. et al. Leiomyosarcoma of the urinary bladder: a SEER database study and comparison to leiomyosarcomas of the uterus and extremities/trunk. Ann Diagn Pathol 2021;53:151743. DOI: 10.1016/j.anndiagpath.2021.151743.
6. Rodríguez D., Preston M.A., Barrisford G.W. et al. Clinical features of leiomyosarcoma of the urinary bladder: analysis of 183 cases. Urol Oncol 2014;32(7):958–65. DOI: 10.1016/j.urolonc.2014.01.025.
7. Parekh D.J., Jung C., O’Conner J. et al. Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas. Urology 2002;60(1):164. DOI: 10.1016/s0090-4295(02)01701-6.
8. Brucker B., Ernst L., Meadows A., Zderic S. A second leiomyosarcoma in the urinary bladder of a child with a history of retinoblastoma 12 years following partial cystectomy. Pediatr Blood Cancer 2006;46(7):811–4. DOI: 10.1002/pbc.20506.
9. Ramírez Sevilla C., Admella-Salvador C., Romero-Martin J.A. et al. Bladder leiomyosarcoma 25 years after treatment with cyclophosphamide in patient with history of retinoblastoma. Urol Int 2018;100(1): 119–21. DOI: 10.1159/000437442.
10. Tanguay C., Harvey I., Houde M. et al. Leiomyosarcoma of urinary bladder following cyclophosphamide therapy: report of two cases. Mod Pathol 2003;16(5):512–4. DOI: 10.1097/01.MP.0000068237.38715.D9.
11. Oncological Database My Cancer Genome. Available at: https://www.mycancergenome.org/content/disease/leiomyosarcoma/. (In Russ.).
12. Rosser C.J., Slaton J.W., Izawa J.I. et al. Clinical presentation and outcome of highgrade urinary bladder leiomyosarcoma in adults. Urology 2003;61(6):1151–5. DOI: 10.1016/s0090-4295(03)00021-9.
13. Hamadalla N.Y., Rifat U.N., Safi K.C. et al. Leiomyosarcoma of the urinary bladder: a review and a report of two further cases. Arab J Urol 2013;11(2):159–64. DOI: 10.1016/j.aju.2013.03.004.
14. Slaoui H., Sanchez-Salas R., Validire P. et al. Urinary bladder leiomyosarcoma: primary surgical treatment. Urol Case Rep 2014;2(4):137–8. DOI: 10.1016/j.eucr.2014.05.002.
Review
For citations:
Reva I.A., Nyushko K.M., Plekhanova E.N., Sanikovich V.D., Chernushenko A.S., Akhvlediani N.D., Pushkar D.Yu. Bladder leiomyosarcoma originating from the muscular elements of the bladder mucosa (clinical case). Cancer Urology. 2022;18(1):106-111. (In Russ.) https://doi.org/10.17650/1726-9776-2022-18-1-106-111
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