Experience of Cancer Research Center in the treatment of advanced germ cell tumors
https://doi.org/10.17650/1726-9776-2005-1-3-60-65
Abstract
The experience of CRC in the treatment of advanced germ cell tumors is reported. The analysis of factors influencing prognosis and treatment tactics is carried out. Contemporary conception of advanced germ cell tumors treatment implies the initial use of platinum based chemotherapy. After completion of chemotherapy, surgical removal of residual tumor (retroperitoneal and mediastinal lymph nodes, lung and liver metastases) carries diagnostic and curative means. Such approach allows curing 50-90% of patients depending on prognostic factors. Results of induction chemotherapy for relapses of germ cell tumors are presented separately. Treatment of this condition comprises chemotherapy with inclusion of ifosfamid or taxanes with following cytoreductive surgery. This modality allows long term remission in the fourth of patients with relapse of germ cell tumors.
About the Authors
S. A. Tyulyandin
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
A. A. Tryakin
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
A. A. Bulanov
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
K. M. Figurin
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
I. A. Fainshtein
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
B. E. Polotskiy
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
A. V. Mitin
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
T. I. Zaharova
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
A. M. Garin
ГУ РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
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Review
For citations:
Tyulyandin S.A., Tryakin A.A., Bulanov A.A., Figurin K.M., Fainshtein I.A., Polotskiy B.E., Mitin A.V., Zaharova T.I., Garin A.M. Experience of Cancer Research Center in the treatment of advanced germ cell tumors. Cancer Urology. 2005;1(3):60-65. (In Russ.) https://doi.org/10.17650/1726-9776-2005-1-3-60-65
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