Factors of prognosis in cancer of the penis
https://doi.org/10.17650/1726-9776-2005-1-3-55-60
Abstract
Carcinoma of the penis is a rare tumor. With adequate treatment of patients having no late metastases, 5-year survival is as high as 91.6%; 1-year relapse-free survival is 45.9%. Multivariance analysis shows that regional lymph nodal involvement is the only significant poor predictor in penile carcinoma, which reduces 5-year survival rates from 94.4 to 73.9%. Univariance analysis indicates that the partial effect of therapy, the endophytic form of primary tumor growth, a recurrence occurring after achievement of a complete therapeutic effect exert a significant negative action on survival. An insignificant survival reduction is observed in groups of patients less than 30 and more than 60 years with a neoplasm > 4 cm of high T stage being located on the glans et corpus penis.
About the Authors
E. A. KhalafyanRussian Federation
M. I. Volkova
Russian Federation
L. L. Gurariy
Russian Federation
T. I. Zakharova
Russian Federation
V. A. Romanov
Russian Federation
References
1. Burgers J.K., Badalament R.А., Drago J.R. Penile cancer. Clinical presentation, diagnosis and staging // Urol.Clin.N.Amer. — 1992. — Vol.19. — P.247.
2. Cabanas R.M. An approach for the treatment of penile carcinoma // Cancer. — 1977. — Vol.39. — P.456.
3. Rather P., Lutzeyer W. Bleomycin effects on malignant tumors of the male genitalia // Prog. Biochem. Pharm. — 1976. — Vol.11. — Р.223—228.
4. Sharma U., Rath G.K. et al. Megavoltage radiation therapy in carcinoma of the penis // Int. Surg. — 1982. — Vol.67. — Р.69—71.
5. Algaba F., Horenblas S., Pizzocaro-Luigi Piva G. et al. EAU Guidelines on penile cancer // Eur. Urol. — 2002. — Vol.42. — Р.199—203.
6. Soria J.C., Fizazi K., Piron D. et al. Squamous cell carcinoma of the penis: multivariate analysis of prognostic factors and natural history in monometric study with a conservative policy // Ann.Oncol. — 1997. — Vol.8. — P.1089—1098.
7. Rubio-Briones J., Villavicencio H., Regalado R. et al. Squamous cell carcinoma of the penis: treatment protocol accoding to our 14 years of experience // Arch.Esp.Urol. — 1997. — Vol.50. — P.473—480.
8. Puras-Baez A., Rivera-Herrera J. Invasive carcinoma of the penis: management and prognosis // Urologic oncology. Edited by Joseph E. Oesterling, Jerome P. Richie — USA: W. B. Saunders Company. — 1997. — Р. 604—617.
9. Young M.J., Reda D.J., Waters W.B. Penile carcinoma. A twenty-five year experience // Urology. — 1991. — Vol.38. — Р.529—532.
10. Sarin R., Norman A.R., Steel G.G., Horwich A. Treatment results and prognostic factors in 101 men treated for squamous carcinoma of the penis. // Int. J. Radiat. Oncol. Biol. Phys. — 1997. — Vol.38. — Р.713—722.
11. Kulkarni J.N., Kamat M.R. Prophylactic bilateral groin node dissection versus prophylactic radiotherapy and surveillance in patients with N0 and N1—2A carcinoma of the penis // Eur.Urol. — 1994. — Vol.26. — P.123—127.
12. Lindegaard J.C., Nielsen O.S., Lundbeck F.A. et al. A retrospective analysis of 82 cases of cancer of the penis. // Br. J. Urol. — 1996. — Vol. 77. — Р. 883—890.
13. Chiu T.Y., Huang H.S., Lai M.K. et al. Penile cancer in Taiwan-20 years’ experience at National Taiwan University Hospital // J.Formos.Med.Assoc. — 1998. — Vol.97. — P.673—678.
Review
For citations:
Khalafyan E.A., Volkova M.I., Gurariy L.L., Zakharova T.I., Romanov V.A. Factors of prognosis in cancer of the penis. Cancer Urology. 2005;1(3):55-60. (In Russ.) https://doi.org/10.17650/1726-9776-2005-1-3-55-60