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ПОСЛЕДОВАТЕЛЬНАЯ ТЕРАПИЯ МЕТАСТАТИЧЕСКОГО КАСТРАЦИОННО-РЕЗИСТЕНТНОГО РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ: НОВЫЕ ВОЗМОЖНОСТИ

https://doi.org/10.17650/1726-9776-2018-14-3-120-127

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Аннотация

В настоящее время в арсенале врача имеется целый ряд лекарственных препаратов, позволяющих увеличить продолжительность жизни больных кастрационно-резистентным раком предстательной железы (КРРПЖ). Большинство из них разрешены для применения в 1-й линии терапии и признаются потенциально равно эффективными ввиду отсутствия их прямого сравнения. Пациенты, страдающие КРРПЖ, нуждаются в непрерывном лечении для сдерживания прогрессирования заболевания, что требует последовательного применения терапевтических агентов. Современные стандарты и рекомендации не дают четкого алгоритма по назначению лечения, поэтому необходим индивидуальный подход в каждом конкретном случае с учетом разнообразных факторов от характера предшествующей терапии до предпочтений пациента. В настоящей статье рассмотрены роль наиболее значимых факторов, влияющих на выбор терапии, и способы оптимизации терапии КРРПЖ в приложении к установленным стандартам лечения и с учетом списка разрешенных в России препаратов.

Об авторах

А. С. Маркова
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России
Россия

115478 Москва, Каширское шоссе, 24.



В. Б. Матвеев
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России
Россия

115478 Москва, Каширское шоссе, 24.



Б. М. Назранов
ГБУЗ «Городская клиническая больница № 1»
Россия

Кабардино-Балкарская республика, 360004 Нальчик, ул. Головко, 7.



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Для цитирования:


Маркова А.С., Матвеев В.Б., Назранов Б.М. ПОСЛЕДОВАТЕЛЬНАЯ ТЕРАПИЯ МЕТАСТАТИЧЕСКОГО КАСТРАЦИОННО-РЕЗИСТЕНТНОГО РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ: НОВЫЕ ВОЗМОЖНОСТИ. Онкоурология. 2018;14(3):120-127. https://doi.org/10.17650/1726-9776-2018-14-3-120-127

For citation:


Markova A.S., Matveev V.B., Nazranov B.M. SEQUENTIAL THERAPY OF METASTATIC CASTRATION-RESISTANT PROSTATE CANCER: NEW POSSIBILITIES. Cancer Urology. 2018;14(3):120-127. (In Russ.) https://doi.org/10.17650/1726-9776-2018-14-3-120-127

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ISSN 1726-9776 (Print)
ISSN 1996-1812 (Online)