Email this article PROGNOSTIC MARKERS OF URINARY BLADDER CANCER RECURRENCE AND LYMPHATIC SPREAD
- Authors: Pavlov V.N.1, Izmailov A.A.1, Izmailova S.M.1, Urmancev M.F.1, Ahmadishina L.Z.1, Alekseev A.V.1, Zagitov A.R.1, Kutliarov L.M.1, Victorova T.V.1
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Affiliations:
- State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”, Clinical Hospital Bashkirsky Medical State University,Ufa
- Issue: Vol 8, No 1 (2012)
- Pages: 56-61
- Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. URINARY BLADDER CANCER
- Published: 30.03.2012
- URL: https://oncourology.abvpress.ru/oncur/article/view/82
- DOI: https://doi.org/10.17650/1726-9776-2012-8-1-56-61
- ID: 82
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Abstract
Treatment results (2005-2009) for patients with surface (n = 104) and invasive (n = 104) urinary bladder carcinoma were analyzed. Molecular genetic analysis of cytochrome gene P450 polymorphous locus carried out: CYP1А1 (A2455G), СYP1A2 (T-2464delT), Glutathione S-transferase: GSTM1 (del), GSTP1 (A313G); DNA reparation: XRCC1 (G28152A) for patients with surface urine bladder carcinoma recurrence, which took place within a year, and for patients with surface urine bladder carcinoma without recurrence within a year. Genotypes associated with surface urine bladder carcinoma one-year recurrence were identified. Furthermore, analysis of these genes polymorphous locsus of patients with invasive urine bladder carcinoma with and without lymphogenic metastases was carried out. Genotypes associated with lyphogenic metastasis risk were identified.
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About the authors
V. N. Pavlov
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Author for correspondence.
Email: Izmailov75@mail.ru
Russian Federation
A. A. Izmailov
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
S. M. Izmailova
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
M. F. Urmancev
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
L. Z. Ahmadishina
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
A. V. Alekseev
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
A. R. Zagitov
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
L. M. Kutliarov
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
T. V. Victorova
State Educational Institution of Higher Professional Education “Bashkirsky Medical State University”,Clinical Hospital Bashkirsky Medical State University,Ufa
Email: Izmailov75@mail.ru
Russian Federation
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