Malignant paraganglioma of the urinary bladder. Description of clinical cases

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Abstract

Paraganglioma is hormonally active tumor originating from chromaffin tissue of sympathoadrenal system that secrete large amounts of catecholamines. Paraganglioma of the urinary bladder is a rare neoplasm, constituting approximately 0.06 % of all tumors of this localization. It is believed that this disease arises from embryonic remnants of chromaffin cells in the sympathetic plexus of the detrusor. Up to 10 % of these tumors have malignant origin. Diagnosis and tactics of treatment of patients with malignant paragangliomas of the bladder presents certain difficulties. The article describes 2 clinical observations of patients with this bladder pathology. 

About the authors

A. V. Khaylenko

Federal State Budgetary Institution «Russian oncological Research Center named after N.N. Blokhin» of the Russian Ministry of Health;
N.I. Pirogov Russian National Research Medical University at the Ministry of Health of Russia

Author for correspondence.
Email: a.khaylenko@mail.ru

24 Kashirskoye shosse, Moscow, 115478

Department of Oncology the Faculty of Additional Professional Education

1 Ostrovityanova St., Moscow, 117997

Russian Federation

K. M. Figurin

Federal State Budgetary Institution «Russian oncological Research Center named after N.N. Blokhin» of the Russian Ministry of Health

Email: kfigurin@MAIL.RU
24 Kashirskoye shosse, Moscow, 115478 Russian Federation

A. P. Kazantsev

Federal State Budgetary Institution «Russian oncological Research Center named after N.N. Blokhin» of the Russian Ministry of Health

24 Kashirskoye shosse, Moscow, 115478 Russian Federation

D. V. Rybakova

Federal State Budgetary Institution «Russian oncological Research Center named after N.N. Blokhin» of the Russian Ministry of Health

24 Kashirskoye shosse, Moscow, 115478 Russian Federation

A. G. Perevoshchikov

Federal State Budgetary Institution «Russian oncological Research Center named after N.N. Blokhin» of the Russian Ministry of Health

Email: a.khaylenko@mail.ru
24 Kashirskoye shosse, Moscow, 115478 Russian Federation

K. A. Romanova

Federal State Budgetary Institution «Russian oncological Research Center named after N.N. Blokhin» of the Russian Ministry of Health

24 Kashirskoye shosse, Moscow, 115478 Russian Federation

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