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EXPRESSION OF MATRIX METALLOPROTEINASE-9 IN ADENOCARCINOMA OF PROSTATE
- Authors: Andruchin M.I.1, Pulbere S.A.1, Loktev A.V.1, Babichenko I.I.1
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Affiliations:
- Peoples’ Friendship University of Russia, Moscow
- Issue: Vol 10, No 2 (2014)
- Pages: 35-37
- Section: PROSTATE CANCER
- Published: 30.06.2014
- URL: https://oncourology.abvpress.ru/oncur/article/view/51
- DOI: https://doi.org/10.17650/1726-9776-2014-10-2-35-37
- ID: 51
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Abstract
Iimmunohistochemical study of cells proliferative activity by Ki-67 protein and localization of matrix metalloproteinase-9 (MMP-9) has been carried out at benign prostatic hyperplasia and adenocarcinoma of different gradations by the Gleason score. A significant decrease of the MMP-9 levels in the adenocarcinoma of different gradations have been found. A moderate positive correlation between the Gleason score and cell proliferation Ki-67 index (rs = 0.674) and a moderate negative correlation with the level of such score and expression of MMP-9 (rs = –0.660) were detected
About the authors
M. I. Andruchin
Peoples’ Friendship University of Russia, Moscow
Email: doklok@mail.ru
Department of Urology and Operative Nephrology Russian Federation
S. A. Pulbere
Peoples’ Friendship University of Russia, Moscow
Email: doklok@mail.ru
Department of Urology and Operative Nephrology Russian Federation
A. V. Loktev
Peoples’ Friendship University of Russia, Moscow
Author for correspondence.
Email: doklok@mail.ru
Department of Urology and Operative Nephrology Russian Federation
I. I. Babichenko
Peoples’ Friendship University of Russia, Moscow
Email: doklok@mail.ru
Department of Pathological Anatomy Russian Federation
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