CURRENT APPROACHES TO DIAGNOSING PROSTATE CANCER, BY APPLYING MAGNETIC RESONANCE SPECTROSCOPY (A CLINICAL STUDY)

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Abstract

By evaluating abnormal metabolism, magnetic resonance spectroscopy (MRS) is a highly effective tool for diagnosing prostate cancer (PC). Our study has indicated that the level of citrate (Ci) and the ratio of the content of choline (Cho) and creatine (Cr) to that of citrate ((Cho + Cr)/Ci) are the most sensitive and specific indicators. These may be effectively used separately (to diagnose tumor involvement and to determine the degree of tumor differentiation) and as a part of the authors’ discriminant model.

The findings suggest that it is expedient to use MRS in the comprehensive diagnosis of PC.

About the authors

E. A. Moskalenko

Urology Clinic and 2Radiology Clinic of the S.M. Kirov Military Medical Academy, Saint Petersburg

Author for correspondence.
Email: m.lena1976@mail.ru
Russian Federation

S. B. Petrov

Urology Clinic and 2Radiology Clinic of the S.M. Kirov Military Medical Academy, Saint Petersburg

Email: m.lena1976@mail.ru
Russian Federation

Yu. V. Tolkach

Urology Clinic and 2Radiology Clinic of the S.M. Kirov Military Medical Academy, Saint Petersburg

Email: m.lena1976@mail.ru
Russian Federation

A. V. Mishchenko

Клиника рентгенологии и радиологии Военно-медицинской академии им. С.М. Кирова, Санкт-Петербург

Email: m.lena1976@mail.ru
Russian Federation

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