Survival of patients with bladder cancer after radical cystectomy
https://doi.org/10.17650/1726-9776-2016-12-1-29-35
Abstract
Objective: to investigate survival in patients with bladder cancer (BC) after radical cystectomy (RCE).
Subjects and methods. Our clinic performed RCE using different urine derivations in 375 patients with BC. There were 324 (86.4%) men and 51 (13.6%) women. All the patients underwent clinical, laboratory, ultrasound, X-ray, and radiation studies.
Results. The 10-year overall and cancer-specific survival rates were 43.4 and 47.2%, respectively. In patients without regional lymph node (LN) metastases, the 2- and 3-year overall survival rates were 81.2 and 67.2%. In those with regional LN metastases, the 2- and 5-year overall survival rates were 46.9 and 13.9%. In the negative LN group, the 2- and 5-year cancer-specific survival rates were 83.6% and 70.7%, respectively. In the positive LN group, these were 51.0 and 15.1%. The overall and cancer-specific survival rates also declined with higher tumor stage and grade.
Conclusion. Tumor stage, regional LN metastases, and histopathological grade have a considerable independent impact on the overall and cancer-specific survival rates of patients with BC following RCE.
About the Authors
B. K. Komyakov
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
B. G. Guliev
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
A. V. Sergeev
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
V. A. Fadeev
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
A. Yu. Ulyanov
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
Ya. S. Savashinsky
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
S. S. Kasyanenko
I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Department of Urology,
41, Kirochnaya St., Saint Petersburg 191015
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Review
For citations:
Komyakov B.K., Guliev B.G., Sergeev A.V., Fadeev V.A., Ulyanov A.Yu., Savashinsky Ya.S., Kasyanenko S.S. Survival of patients with bladder cancer after radical cystectomy. Cancer Urology. 2016;12(1):29-35. https://doi.org/10.17650/1726-9776-2016-12-1-29-35
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