CLINICALLY LOCALIZED PROSTATE CANCER: CAPACITIES OF MATRIX COIL MRI TO DETECT MINIMAL EXTRACAPSULAR TUMOR SPREAD
https://doi.org/10.17650/1726-9776-2012-8-4-53-57
Abstract
Retrospective assessment of preoperative magnetic resonance imaging (MRI) data in 37 patients with prostate cancer, who had undergone radical prostatectomy, established the most diagnostically valuable MRI signs of minimal extracapsular spread (ECS): asymmetry of neurovascular fascicles (72 % accuracy, 93 % sensitivity, 77 % specificity, 73 % positive and 94% negative predictive values) and iron outline deformity/irregularity (66/80/64/60/82 %, respectively); as well as their higher diagnostic efficiency versus the clinical and laboratory predictors of ECS: total Gleason scores (58/87/55/57/86 %, respectively) and serum PSA levels (uninformative), which permits their consideration while choosing a more or less radical prostatectomy modality.
About the Authors
E. A. Petrova
Medical Radiology Research Center, Ministry of Health of Russia, Obninsk
Russian Federation
Russian Federation
T. P. Berezovskaya
Medical Radiology Research Center, Ministry of Health of Russia, Obninsk
Russian Federation
Russian Federation
O. B. Karyakin
Medical Radiology Research Center, Ministry of Health of Russia, Obninsk
Russian Federation
Russian Federation
D. V. Neledov
Medical Radiology Research Center, Ministry of Health of Russia, Obninsk
Russian Federation
Russian Federation
N. A. Gorban
Medical Radiology Research Center, Ministry of Health of Russia, Obninsk
Russian Federation
Russian Federation
Z. N. Shavladze
Medical Radiology Research Center, Ministry of Health of Russia, Obninsk
Russian Federation
Russian Federation
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Review
For citations:
Petrova E.A., Berezovskaya T.P., Karyakin O.B., Neledov D.V., Gorban N.A., Shavladze Z.N. CLINICALLY LOCALIZED PROSTATE CANCER: CAPACITIES OF MATRIX COIL MRI TO DETECT MINIMAL EXTRACAPSULAR TUMOR SPREAD. Cancer Urology. 2012;8(4):53-57. (In Russ.) https://doi.org/10.17650/1726-9776-2012-8-4-53-57
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