Email this article CLINICAL SIGNIFICANCE OF SOME IMMUNOHISTOCHEMICAL MARKERS IN NON-MUSCLE-INVASIVE BLADDER CARCINOMA
- Authors: Safiullin K.N.1, Gorban N.A.1, Karyakin O.B.1, Pugachev V.V.1
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Affiliations:
- Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk
- Issue: Vol 6, No 4 (2010)
- Pages: 36-41
- Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. URINARY BLADDER CANCER
- Published: 30.12.2010
- URL: https://oncourology.abvpress.ru/oncur/article/view/331
- DOI: https://doi.org/10.17650/1726-9776-2010-6-4-36-41
- ID: 331
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Abstract
The prognostic value of the expression of c-erbB-2 oncoprotein, p53 protein, cytokeratin 20, and Ki-67 was estimated in papillary urothelial non-muscle-invasive bladder carcinoma (BC). The biopsy and surgery samples from 57 patients (46 males and 11 females) aged 24 to 75 years (mean age 56±1.5 years), who received combination treatment for non-muscle-invasive BC, were examined. It has been found that с-erbB-2 and р53 are important prognostic markers of non-muscle-invasive BC. Co-expression of 3 markers is of high statistic significance.
About the authors
K. N. Safiullin
Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk
Author for correspondence.
Email: perovanina@mail.ru
Russian Federation
N. A. Gorban
Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk
Email: perovanina@mail.ru
Russian Federation
O. B. Karyakin
Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk
Email: perovanina@mail.ru
Russian Federation
V. V. Pugachev
Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk
Email: perovanina@mail.ru
Russian Federation
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