REPEATED TRANSRECTAL PROSTATE BIOPSY IN PATIENTS WITH ATYPICAL SMALL ACINA

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Abstract

Objective: to define the optimal time and technique of repeated transrectal prostate biopsy (RTPB) in patients with atypical small acinar proliferation (ASAP).

Subjects and methods: RTPB was performed in 210 patients with first diagnosed ASAP. The study was conducted on an average 8 (range 1 to 12) months after the first biopsy and involved 12, 14, 16, and 18 biopsy cores.  

Results: According to the results of repeated biopsy, prostate adenocarcinoma was verified in 64.8% (136/210) of cases. The highest detection rate was found with biopsy schemes including 16 and 18 cores 1 and 3 months after the first biopsy (p < 0.05).  

Conclusions: ASAP is a precursor of prostate cancer and its presence in the morphological specimen during the first biopsy requires RTBT in the early periods irrespective of PSA levels.

 

About the authors

M. A. Kurdzhiev

Department of Urology, Moscow State University of Medicine and Dentistry

Author for correspondence.
Email: mkurd@mail.ru
Кафедра урологии Russian Federation

A. V. Govorov

Department of Urology, Moscow State University of Medicine and Dentistry

Email: mkurd@mail.ru
Кафедра урологии Russian Federation

M. V. Kovylina

Department of Urology, Moscow State University of Medicine and Dentistry

Email: mkurd@mail.ru
Кафедра урологии Russian Federation

D. Yu. Pushkar

Department of Urology, Moscow State University of Medicine and Dentistry

Email: mkurd@mail.ru
Кафедра урологии Russian Federation

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