Email this article 
PHOTODYNAMIC DIAGNOSIS AND FLUORESCENCE SPECTROSCOPY IN SUPERFICIAL BLADDER CANCER
- Authors: Rusakov I.G.1, Sokolov V.V.1, Bulgakova N.N.2, Teplov A.A.1, Ulyanov R.V.1
-
Affiliations:
- P.A. Herzen Moscow Research Oncological Institute
- M.A. Prokhorov General Physics Institute, Russian Academy of Science, Moscow
- Issue: Vol 5, No 4 (2009)
- Pages: 41-46
- Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS
- Published: 30.12.2009
- URL: https://oncourology.abvpress.ru/oncur/article/view/296
- DOI: https://doi.org/10.17650/1726-9776-2009-5-4-41-46
- ID: 296
Cite item
Full Text
Abstract
A comprehensive fluorescence technique has been developed to study the urinary bladder mucosa in patients with superficial bladder cancer (BC), by using alasense, white light cystoscopy, fluorescence cytoscopy, and local fluorescence spectroscopy in vivo. Quantification of urothelium fluorescence in the red emission foci of 5-ALA-induced protophorphyrin, with the local autofluorescence intensity being borne in mind, has been shown to increase the specificity of photodynamic diagnosis of superficial BC from 70 to 85% (p ≤ 0.05) and the total accuracy of the technique from 80 to 86%.
About the authors
I. G. Rusakov
P.A. Herzen Moscow Research Oncological Institute
Author for correspondence.
Email: rusakov@hotmail.ru
Russian Federation
V. V. Sokolov
P.A. Herzen Moscow Research Oncological Institute
Email: rusakov@hotmail.ru
Russian Federation
N. N. Bulgakova
M.A. Prokhorov General Physics Institute, Russian Academy of Science, Moscow
Email: rusakov@hotmail.ru
Russian Federation
A. A. Teplov
P.A. Herzen Moscow Research Oncological Institute
Email: rusakov@hotmail.ru
Russian Federation
R. V. Ulyanov
P.A. Herzen Moscow Research Oncological Institute
Email: rusakov@hotmail.ru
Russian Federation
References
Supplementary files
