PROGNOSTIC SIGNIFICANCE OF KI-67, MMP-9 AND COL IV IMMUNOHISTOCHEMICAL MARKERS AT BLADDER TUMORS

V. P. Avdoshin; Авдошин В. П.; I. I. Babichenko; Бабиченко И. И.; E. V. Kotelnikova; Котельникова Е. В.

doi:10.17650/1726-9776-2011-7-3-75-79

PROGNOSTIC SIGNIFICANCE OF KI-67, MMP-9 AND COL IV IMMUNOHISTOCHEMICAL MARKERS AT BLADDER TUMORS

Authors: Avdoshin V.P.¹, Babichenko I.I.¹, Kotelnikova E.V.¹
Affiliations:
1. Russian Peoples,Friendship Universiti, Moskow
Issue: Vol 7, No 3 (2011)
Pages: 75-79
Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. URINARY BLADDER CANCER
Published: 30.09.2011
URL: https://oncourology.abvpress.ru/oncur/article/view/238
DOI: https://doi.org/10.17650/1726-9776-2011-7-3-75-79
ID: 238

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Abstract

The prognostic value of the expression Ki-67, ММР-9 and collagen IV were estimated in urotelial bladder tumors. The biopsy and surgery samples from 43 patients (27 males and 16 females ) aged 42 to 87 years (mean age 66 ± 1.5 years) who received combination treatment for urotelial tumors. It has been found that Ki-67, ММР-9 and collagen IV are important prognostic markers of urotelial invasive bladder carcinoma.