THE DISORDER OF KATHECHOLAMINE METABOLISM AFTER A KIDNEY RESECTION AND NEPHRECTOMY IN THE EXPERIMENT

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Abstract

The experimental modeling of a kidney resection and nephrectomy in a series on 100 laboratory rats in comparison with group of the control animals has revealed essential authentic (p < 0,05) the disorder of kathecholamine metabolism not only in operating kidney, but also in opposite, and also in heart and Central nerve System. As a result of 30-day's supervision over animals is revealed, that the specified the disorder of kathecholamine metabolism in the early postoperative period after nephrectomy are expressed much in the greater degree and up to the end of experiment is saved in comparison with group of a kidney resection, in which by 30 day of experience all investigated parameters were normalized. The given study is an experimental substantiation the greater pathophysiological safety of a kidney resection in comparison with nephrectomy.

About the authors

A. P. Ivanov

Yaroslavl State Medical Academy

Email: phoenix-67@list.ru
Russian Federation

V. N. Fedorov

Yaroslavl State Medical Academy

Email: phoenix-67@list.ru
Russian Federation

I. V. Chernyshev

Research Institute of Urology, Ministry of Health and Social Development of Russia, Moscow

Email: phoenix-67@list.ru
Russian Federation

I. A. Tyuzikov

Medical Center of Diagnosis and Prevention, Yaroslavl

Author for correspondence.
Email: phoenix-67@list.ru
Russian Federation

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