Review of the effectiveness of nuclear magnetic resonance spectroscopy for prostate cancer diagnosis
https://doi.org/10.17650/1726-9776-2025-21-2-182-191
Abstract
Prostate cancer (PCa) is the most common malignant neoplasm among men in Russia and one of the most common worldwide. PCa diagnosis, progression management, and evaluation of prognosis are performed using a combination of examinations: laboratory, instrumental, and various nomograms. The current methods of PCa diagnosis have limited sensitivity and specificity, therefore the search for new diagnostic methods is an important problem. Nuclear magnetic resonance (NMR) spectroscopy is a promising method allowing to detect malignant tumor-associated metabolites in biological liquids. According to some studies, PCa is associated with changes in levels of various metabolites in serum and plasma. This review presents the results of studies reporting on high effectiveness of NMR spectroscopy analysis of serum and plasma for PCa diagnosis.
About the Authors
V. M. Perepukhov
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
Vladimir Maksimovich Perepukhov
Build. 1, 51 3rd Parkovaya St., Moscow 105425
K. M. Nyushko
N.A. Lopatkin Research Institute of Urology and Interventional Radiology – branch of the National Medical Research Radiological Center, Ministry of Health of Russia; Medical Institute of Continuing Education, Russian Biotechnological University
Russian Federation
Russian Federation
Build. 1, 51 3rd Parkovaya St., Moscow 105425;
11 Volokolamskoe Shosse, Moscow 125080
B. Ya. Alekseev
Medical Institute of Continuing Education, Russian Biotechnological University;
National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
11 Volokolamskoe Shosse, Moscow 125080;
3 2nd Botkinskiy Proezd, Moscow 125284
O. A. Mailyan
National Medical Research Radiological Center, Ministry of Health of Russia
Russian Federation
Russian Federation
3 2nd Botkinskiy Proezd, Moscow 125284
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Review
For citations:
Perepukhov V.M., Nyushko K.M., Alekseev B.Ya., Mailyan O.A. Review of the effectiveness of nuclear magnetic resonance spectroscopy for prostate cancer diagnosis. Cancer Urology. 2025;21(2):182-191. (In Russ.) https://doi.org/10.17650/1726-9776-2025-21-2-182-191
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