Preview

Cancer Urology

Advanced search

Organ-preserving surgery: current line of therapy in children with nephroblastoma (a review of the literature and the author's own clinical findings)

https://doi.org/10.17650/1726-9776-2007-0-2-18-25

Abstract

Nephroblastoma (NB) is a tumor that frequently occurs in childhood. Progress in therapy of NB is associated with the development of modern radio and chemotherapy. Contemporary chemotherapy allows for an organ-preserving treatment of patients with NB. The author’s experience gained at the Research Institute of Pediatric Oncology and Hematology (RIPOH), N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences is presented. Data on 120 patients aged 6 months to 12 months, who were treated with organ-preserving operations of different types and extent, are analyzed. A clinical classification of NB in children and a working classification of bilateral NB, which has been developed at the RIPOH, are provided. The technique of different types of organ-preserving surgery in children with NB is described as well as the long-term results of treatment.

About the Author

T. A. Sharoyev
Research Institute of Pediatric Oncology and Hematology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Moscow


References

1. Дурнов Л.А., Шароев Т.А. Рабдомиосаркомы у детей. Оренбург, Южный Урал; 1997. с. 23.

2. Лопаткин Н.А., Пугачев А.Г. Детская урология: Руководство. М., Медицина; 1986.

3. Пугачев А.Г., Москалев И.Н. Эволюция функции почек у взрослых, оперированных в детстве по поводу гидронефроза. Махачкала; 2003. с. 142—3.

4. Пугачев А.Г. Органосохраняющие операции — основное направление в детской урологии. Урология 2004;(4):3—5.

5. Cozzi F., Schiavetti A., Morini F., Cozzi D.A. Re: partial nephrectomy for unilateral Wilms tumor: results of study SIOP 93-01/GPOH. J Urol 2004;171(6 Pt 1):2383.

6. Cozzi F., Schiavetti A., Bonnanni M. et al. Enucleative surgery for stage I nephroblastoma with a normal contralateral kidney. J Urol 1996;156(5):1788—93.

7. Gruner M., Chaouachi B., Bitker M., Gibbod L.B. The place of concervative surgery in the treatment of nephroblastomas. J Urol (Paris) 1982;88(4):223—9.

8. Haecker F.M., von Schweinitz D., Harms D. et al. Partial nephrectomy for unilateral Wilms tumor: results of study SIOP 93-01/GPOH. J Urol 2003;170:939—44.


Review

For citations:


Sharoyev T.A. Organ-preserving surgery: current line of therapy in children with nephroblastoma (a review of the literature and the author's own clinical findings). Cancer Urology. 2007;3(2):18-25. (In Russ.) https://doi.org/10.17650/1726-9776-2007-0-2-18-25

Views: 289


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1726-9776 (Print)
ISSN 1996-1812 (Online)
X