Email this article THE SHORT-TERM PERFORMANCE RESULTS OF PROSTATE ADENOCARCINOMA MULTIMODAL TREATMENT IN NOVOSIBIRSK REGION
- Authors: Kunin I.S.1,2, Korotkov E.A.1, Aidagulova S.V.1, Seryapina Y.V.1, Anikeeva О.Y.1,3, Vorobjeva Т.G.3, Bedniy I.V.3, Narov Y.E.1, Ivaninskiy О.I.2, Marinkin I.О.1
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Affiliations:
- Novosibirsk State Medical University
- Novosibirsk Regional Oncologic Clinics, Mimistry of Health of Russia
- E.N. Meshalkin Research Institute of Circulation Pathology, Mimistry of Health of Russia, Novosibirsk
- Issue: Vol 9, No 3 (2013)
- Pages: 59-63
- Section: PROSTATE CANCER
- Published: 30.09.2013
- URL: https://oncourology.abvpress.ru/oncur/article/view/123
- DOI: https://doi.org/10.17650/1726-9776-2013-9-3-59-63
- ID: 123
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Abstract
The short-term performance criteria (PSA blood level and prostate volume) were analyzed concerning the complex (hormonal and radiation) treatment of 57 patients with prostate adenocarcinoma, stratified into three disease progression risk groups. Two treatment regimens were differed in the duration of neoadjuvant hormone therapy: 9 or 32 ± 13 months in combination with external beam radiation therapy with a total dose 76–80 Gy. Statistical analysis of the multimodal treatment efficiency criteria of patients with high risk of prostate adenocarcinoma showed the best result (significant decrease of PSA blood level) using a single 9-month course of hormone therapy and subsequent external beam radiation therapy. The prostate volume indicator in the applicable mode of radiation therapy has mixed dynamics, and requires further study as a multimodal treatment effectiveness criterion.
About the authors
I. S. Kunin
Novosibirsk State Medical University;Novosibirsk Regional Oncologic Clinics, Mimistry of Health of Russia
Author for correspondence.
Email: I.S.Kunin@ngs.ru
Russian Federation
E. A. Korotkov
Novosibirsk State Medical University
Email: I.S.Kunin@ngs.ru
Russian Federation
S. V. Aidagulova
Novosibirsk State Medical University
Email: I.S.Kunin@ngs.ru
Russian Federation
Yu. V. Seryapina
Novosibirsk State Medical University
Email: I.S.Kunin@ngs.ru
Russian Federation
О. Yu. Anikeeva
Novosibirsk State Medical University;E.N. Meshalkin Research Institute of Circulation Pathology, Mimistry of Health of Russia, Novosibirsk
Email: I.S.Kunin@ngs.ru
Russian Federation
Т. G. Vorobjeva
E.N. Meshalkin Research Institute of Circulation Pathology, Mimistry of Health of Russia, Novosibirsk
Email: I.S.Kunin@ngs.ru
Russian Federation
I. V. Bedniy
E.N. Meshalkin Research Institute of Circulation Pathology, Mimistry of Health of Russia, Novosibirsk
Email: I.S.Kunin@ngs.ru
Russian Federation
Yu. E. Narov
Novosibirsk State Medical University
Email: I.S.Kunin@ngs.ru
Russian Federation
О. I. Ivaninskiy
Novosibirsk Regional Oncologic Clinics, Mimistry of Health of Russia
Email: I.S.Kunin@ngs.ru
Russian Federation
I. О. Marinkin
Novosibirsk State Medical University
Email: I.S.Kunin@ngs.ru
Russian Federation
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