Study of the prognostic value of effector cells of the stroma of transitional cell bladder carcinomas
https://doi.org/10.17650/1726-9776-2007-3-4-26-30
Abstract
The prognostic value of number and composition of stromal effector cells in specimens removed during radical surgical treatment for transitional cell bladder carcinoma (Ta-4NxM0) was studied. Higher 5-year survival and less risk of recurrence corresponded to the lower count of effector cells (p = 0.007): lymphocytes (p = 0.024 and p = 0.057) and segmented leukocytes (p = 0.037 and p = 0.042). In patients without progressive cancer, the independent predictors of 5-year survival were the degree of homogeneous mast cell distribution (p = 0.041) and the count stromal lymphocytes (p = 0.070) while in those with stage pTa-pT1, these were the number of segmented leukocytes (p = 0.009) and lymphocytes (p = 0.025) of the stroma (R2 = 0.32; p = 0.008).
About the Authors
A. S. Al-Shukri
Acad. I.P. Pavlov Saint Petersburg State Medical University
Russian Federation
Russian Federation
Department of Urology
I. A. Korneyev
Acad. I.P. Pavlov Saint Petersburg State Medical University
Russian Federation
Russian Federation
Department of Urology
S. Kh. Al-Shukri
Acad. I.P. Pavlov Saint Petersburg State Medical University
Russian Federation
Russian Federation
Department of Urology
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Review
For citations:
Al-Shukri A.S., Korneyev I.A., Al-Shukri S.Kh. Study of the prognostic value of effector cells of the stroma of transitional cell bladder carcinomas. Cancer Urology. 2007;3(4):26-30. (In Russ.) https://doi.org/10.17650/1726-9776-2007-3-4-26-30
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