Definition of the efficacy of prostate cancer treatment within the near terms
https://doi.org/10.17650/1726-9776-2008-4-2-57-61
Abstract
In view of necessity to execute the complex estimation of the methods of the prostate cancer (PC) treatment within the near terms, an integral value of the treatment efficacy is suggested – coefficient of the treatment efficacy. To calculate it the one needs to know a value of increase of the prostate specific antigen level, prostate volume, residual urine amount and the value of the scale of estimation of disturbances of urination IPSS for a fixed time. Coefficient of the treatment efficacy is calculated by calculating of the quotient of the product of the values increases by the sum of the valued increases. To standardize estimation of the treatment efficacy, the calculation of scale of the efficacy with evaluating low, medium and high levels of efficacy is performed.
Estimation of the different variants of treatment of PC depending on advance of the pathologic process in 468 patients is executed.
About the Authors
A. V. Vazhenin
Chelyabinsk regional oncologic clinic, Russian scientific center of radiology and nuclear medicine
Russian Federation
Moscow
Russian Federation
Moscow
P. A. Karnauh
Chelyabinsk regional oncologic clinic, Russian scientific center of radiology and nuclear medicine
Russian Federation
Moscow
Russian Federation
Moscow
References
1. Ткачев С.И. Лучевая терапия рака предстательной железы. Клиническая онкоурология. Под ред. Б.П. Матвеева. М., Вердана; 2003. с. 525–46.
2. Michalski J.M. External beam radiation therapy. Prostate cancer: Principles and practice. Ed. by P.W. Kantoff, P.R. Carroll, A.V. D'Amico. Philadelphia, Baltimore, LWW; 2002. p. 317–35.
3. Partin A.W., Yoo J., Carter H. et al. The use of prostate specific antigen clinical stage and Gleason score to predict pathological stage in men with localized prostate cancer. J Urol 1993;150:110–14.
4. Partin A.W., Kattan M.W., Subong E.N. et al. Combination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer: a multi-institutional update. JAMA 1997;18:1445–51.
5. Roach M., Pickett B., Rosenthal S.A. et al. Defining treatment margins for six field conformal irradiation of localized prostate carcinoma. Int J Radiat Oncol Biol Phys 1994;28:267–75.
6. WHO handbook for reporting results of cancer treatment. Geneva (Switzerland). World Health Organization Offset Publication _ 48. Geneva; 1979.
7. Therasse P., Arbuck S.G., Eisenhauer E.A. et al. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 2000;92(3):205–16.
8. Матвеев Б.П., Бухаркин Б.В., Матвеев В.Б. Рак предстательной железы. М.; 1999.
Review
For citations:
Vazhenin A.V., Karnauh P.A. Definition of the efficacy of prostate cancer treatment within the near terms. Cancer Urology. 2008;4(2):57-61. (In Russ.) https://doi.org/10.17650/1726-9776-2008-4-2-57-61
Views:
228
Email this article 