Expression of platelet-derived growth factor alpha and beta genes PDGFRA and PDGFRB associated with biochemical recurrence of prostate cancer after radical prostatectomy
- Authors: Shkurnikov M.Y.1, Alekseev B.Y.1
-
Affiliations:
- P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
- Issue: Vol 13, No 4 (2017)
- Pages: 45-50
- Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS. PROSTATE CANCER
- Published: 30.12.2017
- URL: https://oncourology.abvpress.ru/oncur/article/view/764
- DOI: https://doi.org/10.17650/1726-9776-2017-13-4-45-50
- ID: 764
Cite item
Abstract
We performed genome-wide transcriptome meta-analysis of prostate cancer samples after radical prostatectomy of patients without lymph node metastasis. Significant associations were determined between expression of platelet-derived growth factor alpha and beta genes (PDGFRA and PDGFRB) and probability and time of onset of biochemical recurrence.
About the authors
M. Yu. Shkurnikov
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Author for correspondence.
Email: mshkurnikov@imscs.msu.ru
3 2nd Botkinskiy Proezd, Moscow 125284 Russian Federation
B. Ya. Alekseev
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia3 2nd Botkinskiy Proezd, Moscow 125284 Russian Federation
References
Supplementary files

