Email this article Dual-stage 18F-fluorocholine PET/CT scanning for biochemical recurrences of prostate cancer
- Authors: Dolgushin M.B.1,2, Odzharova A.A.1,2, Mikhailov A.I.1,2, Shiryaev S.V.3,2, Tulin P.E.1,2, Nevzorov D.I.1,2, Matveev V.B.4,2
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Affiliations:
- Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center
- 23, Kashirskoe Shosse, Moscow 115478, Russia
- Depatment of Radionuclide Diagnosis and Radionuclide Therapy N.N. Blokhin Russian Cancer Research Center
- Urology Department, N.N. Blokhin Russian Cancer Research Center
- Issue: Vol 11, No 2 (2015)
- Pages: 46-54
- Section: PROSTATE CANCER
- Published: 30.06.2015
- URL: https://oncourology.abvpress.ru/oncur/article/view/453
- DOI: https://doi.org/10.17650/1726-9776-2015-11-2-46-54
- ID: 453
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Abstract
PET/CT with 18F-fluorocholine, based on an assessment of phosphatidylcholine biodistribution, is an effective method in the diagnosis of biochemical recurrence of prostate cancer. According to results of our study on 71 patients (PSA level 1,775 (0.0245, 56.0975) ng/mL), the sensitivity of two-stage PET/CT with 18F-fluorocholine was 66.7 % (CI 55.3–78 0 %), and specificity – 80 % (CI 44.9–100.0 %), the overall accuracy of the method ranged from 56.7 to 78.5 %. The results show the feasibility of two-staged PET/CT with 18F-fluorocholine in biochemical recurrence of prostate cancer.
About the authors
M. B. Dolgushin
Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, RussiaRussian Federation
A. A. Odzharova
Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, RussiaRussian Federation
A. I. Mikhailov
Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, Russia
Author for correspondence.
Email: azatmihailov@gmail.com
Russian Federation
S. V. Shiryaev
Depatment of Radionuclide Diagnosis and Radionuclide Therapy N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, RussiaRussian Federation
P. E. Tulin
Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, RussiaRussian Federation
D. I. Nevzorov
Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, RussiaRussian Federation
V. B. Matveev
Urology Department, N.N. Blokhin Russian Cancer Research Center; 23, Kashirskoe Shosse, Moscow 115478, RussiaRussian Federation
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