ПЭТ/КТ с 18F-фторхолином в режиме двухэтапного сканирования при биохимических рецидивах рака предстательной железы
https://doi.org/10.17650/1726-9776-2015-11-2-46-54
Аннотация
Позитронная эмиссионная томографии/компьютерная томография (ПЭТ/КТ) с 18F-фторхолином, основанная на оценке биораспределения фосфатидилхолина, является эффективным методом диагностики при биохимических рецидивах рака предстательной железы (РПЖ). По результатам нашего исследования, основанном на анализе 71 наблюдения пациентов с биохимическим рецидивом РПЖ (уровень простатспецифического антигена в сыворотке крови 1,775 (0,0245; 56,0975) нг/мл, чувствительность двухэтапной ПЭТ/КТ с 18F-фторхолином составила 66,7 %, доверительный интервал (ДИ) 55,3–78,0, при специфичности 80 % (ДИ 44,9–100,0), общая точность метода колебалась от 56,7 до 78,5 %. Полученные результаты свидетельствуют о целесообразности применения ПЭТ/КТ с 18F-фторхолином в режиме двухэтапного сканирования при биохимических рецидивах РПЖ.
Об авторах
М. Б. ДолгушинРоссия
А. А. Оджарова
Россия
А. И. Михайлов
Россия
С. В. Ширяев
Россия
П. Е. Тулин
Россия
Д. И. Невзоров
Россия
В. Б. Матвеев
Россия
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Рецензия
Для цитирования:
Долгушин М.Б., Оджарова А.А., Михайлов А.И., Ширяев С.В., Тулин П.Е., Невзоров Д.И., Матвеев В.Б. ПЭТ/КТ с 18F-фторхолином в режиме двухэтапного сканирования при биохимических рецидивах рака предстательной железы. Онкоурология. 2015;11(2):46-54. https://doi.org/10.17650/1726-9776-2015-11-2-46-54
For citation:
Dolgushin M.B., Odzharova A.A., Mikhailov A.I., Shiryaev S.V., Tulin P.E., Nevzorov D.I., Matveev V.B. Dual-stage 18F-fluorocholine PET/CT scanning for biochemical recurrences of prostate cancer. Cancer Urology. 2015;11(2):46-54. (In Russ.) https://doi.org/10.17650/1726-9776-2015-11-2-46-54