NONINVASIVE DIAGNOSIS OF URINARY BLADDER CANCER BY CROSS-POLARIZATION OPTICAL COHERENCE TOMOGRAPHY: CLINICAL RESULTS

Cover Page

Cite item

Full Text

Abstract

The investigation examined the feasibility of cross-polarization optical cohe-rence tomography (CP OCT) to detect early urinary bladder cancer (UBC). Studies were performed in 376 patients; 5290 images were obtained using an OCT 133-U optical coherence tomograph. To acquire and compare intrared-light scattering images in baseline and orthogonal polarizations is the basis of CP OCT; their analysis makes it possible to judge from the state of the epithelium/connective tissue system and to obtain information on changes in tissue depolarizing components, collagen in particular. The authors elaborated criteria as determinants of the nature of CP OCT changes in direct and orthogonal polarizations in health, inflammatory changes, and UBC at its early stage - urothelial dysplasia and carcinoma in situ in flat suspected areas.

About the authors

O. S. Streltsova

Department of Urology

Author for correspondence.
Email: strelzova_uro@mail.ru
Russian Federation

N. D. Gladkova

Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

E. B. Kiseleva

Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

M. M. Karabut

Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

E. A. Tararova

Department of Urology

Email: strelzova_uro@mail.ru
Russian Federation

K. E. Yunusova

Department of Morbid Anatomy

Email: strelzova_uro@mail.ru
Russian Federation

V. N. Krupin

Department of Urology

Email: strelzova_uro@mail.ru
Russian Federation

E. V. Zagainova

Research Institute of Applied and Fundamental Medicine, Nizhni Novgorod State Medical Academy

Email: strelzova_uro@mail.ru
Russian Federation

References

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c)



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-36986 от  21.07.2009.