Fumarates in the prevention of hypoxic and reperfusion kidney injury: how far is it to surgery? Review of the article “Expanding the indications of antihypoxant infusion solution of sodium fumarate in kidney cancer surgery: literature review”
- Authors: Perlin D.V.1,2
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Affiliations:
- Volgograd State Medical University, Ministry of Health of Russia
- Volgograd Regional Uronephrology Center
- Issue: Vol 21, No 2 (2025)
- Pages: 180-181
- Section: REVIEWS
- Published: 06.08.2025
- URL: https://oncourology.abvpress.ru/oncur/article/view/1963
- DOI: https://doi.org/10.17650/1726-9776-2025-21-2-180-181
- ID: 1963
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About the authors
D. V. Perlin
Volgograd State Medical University, Ministry of Health of Russia;Volgograd Regional Uronephrology Center
Author for correspondence.
D.V. Perlin, MD, PhD, Professor
Russian FederationReferences
- Liu N.W., Khurana K., Sudarshan S. et al. Repeat partial nephrectomy on the solitary kidney: surgical, functional, and oncologic outcomes. J Urol 2010;183(5):1719–24. doi: 10.1016/j.juro.2010.01.010
- Gill I.S., Eisenberg M.S., Aron M. et al. “Zero ischemia” partial nephrectomy: novel laparoscopic and robotic technique. Eur Urol 2011;59(1):128–34. doi: 10.1016/j.eururo.2010.10.002
- Oh C.J., Kim M.J., Lee J.M. et al. Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusion. Kidney Int 2023;104(4):724–39. doi: 10.1016/j.kint.2023.06.022
- Ragab D., Abdallah D.M., El-Abhar H.S. The dual renoand neuro-protective effects of dimethyl fumarate against uremic encephalopathy in a renal ischemia/reperfusion model. Pharmacol Rep 2020;72(4):969–83. doi: 10.1007/s43440-020-00076-4
- Zhen X., Jindong L., Yang Z. et al. Activation of Nrf2 pathway by dimethyl fumarate attenuates renal ischemia-reperfusion injury. Transplant Proc 2021;53(7):2133–9. doi: 10.1016/j.transproceed.2021.07.017
- Ploetz C., Janssen H., Zakrzewicz A. et al. Fumarate in the preservation solution aggravates chronic allograft nephropathy. J Surg Res 2011;166(2):306–13. doi: 10.1016/j.jss.2009.05.044
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