Bilateral urothelial carcinoma of the renal pelvis
- Authors: Gilivanova G.V.1, Kipriyanov E.A.1,2, Karnaukh P.A.2, Ivakhno K.Y.1, Peretrukhin A.A.1, Zolotykh M.A.1, Beydzhanov M.T.1, Rostovtsev D.M.1,2
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Affiliations:
- Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
- South Ural State Medical University, Ministry of Health of Russia
- Issue: Vol 20, No 3 (2024)
- Pages: 136-141
- Section: CLINICAL CASE
- Published: 22.11.2024
- URL: https://oncourology.abvpress.ru/oncur/article/view/1783
- DOI: https://doi.org/10.17650/1726-9776-2024-20-3-136-141
- ID: 1783
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Abstract
Urothelial carcinoma is the 4th most prevalent malignant tumor after prostate (or breast), lung and colorectal cancers. Urothelial carcinoma of the upper urinary tract is quite rare and accounts for 5–10 % of all cases of this type of cancer. Tumors of the renal pelvis are 2 times more common than tumors of the ureter. A clinical case of a 69-year-old patient diagnosed with urothelial carcinoma of the left renal pelvis T2N0M1, stage IV and metastases into the bladder, right renal pelvis is presented. On 08.06.2023, the patient underwent transurethral resection of the bladder tumor, ureteric orifice, nephroureterectomy on the left, retroperitoneal lymphadenectomy. Between 07.2023 and 10.2023, the patient received 6 cycles of chemotherapy according to the following scheme: gemcitabine 1000 mg/m2 intravenously on the 1st and 8th days ++ carboplatin AUC 5 intravenously on the 1st day. Since 11.2023, the patient in receiving maintenance therapy with avelumab.
About the authors
G. V. Gilivanova
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
Author for correspondence.
Email: galina.gpp@gmail.com
ORCID iD: 0000-0001-7674-694X
Galina V. Gilivanova
42 Blukhera St., Chelyabinsk 454000
Russian FederationE. A. Kipriyanov
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine;South Ural State Medical University, Ministry of Health of Russia
Email: kiprijanov@list.ru
ORCID iD: 0000-0002-9403-4345
Evgeny A. Kipriyanov
Department of Oncology, Radiodiagnostics and Radiotherapy, South Ural State Medical University, Ministry of Health of Russia
42 Blukhera St., Chelyabinsk 454000,
64 Vorovskogo St., Chelyabinsk 454141
Russian FederationP. A. Karnaukh
South Ural State Medical University, Ministry of Health of Russia
Email: oncourochel@rambler.ru
ORCID iD: 0009-0009-7866-4513
Karnaukh Peter A.
Department of Oncology, Radiodiagnostics and Radiotherapy
64 Vorovskogo St., Chelyabinsk 454141
Russian Federation
K. Yu. Ivakhno
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
Email: ivakhno1979@mail.ru
ORCID iD: 0000-0003-3843-486X
Konstantin Yu. Ivakhno
42 Blukhera St., Chelyabinsk 454000
Russian FederationA. A. Peretrukhin
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
Email: sosiska-84@mail.ru
ORCID iD: 0009-0002-5204-7524
Andrey A. Peretrukhin
42 Blukhera St., Chelyabinsk 454000
Russian FederationM. A. Zolotykh
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
Email: urogb1@mail.ru
ORCID iD: 0009-0001-3505-9710
Maxim A. Zolotykh
42 Blukhera St., Chelyabinsk 454000
Russian FederationM. T. Beydzhanov
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
Email: bedganovbl22@gmail.com
ORCID iD: 0009-0003-0951-4825
Marif T. Beydzhanov
42 Blukhera St., Chelyabinsk 454000
Russian FederationD. M. Rostovtsev
Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine;South Ural State Medical University, Ministry of Health of Russia
Department of Oncology, Radiodiagnostics and Radiotherapy, South Ural State Medical University, Ministry of Health of Russia
42 Blukhera St., Chelyabinsk 454000,
64 Vorovskogo St., Chelyabinsk 454141
Russian FederationReferences
- Urothelial carcinoma of the upper urinary tract. List of clinical guidelines of the Ministry of Health of Russia. Available at: http://cr.rosminzdrav.ru/recomend/12_3 (In Russ.).
- Malignant tumors in Russia in 2021 (morbidity and mortality). Eds.: А.D. Kaprin, V.V. Starinskiy, A.O. Shakhzadova. Moscow: MNIOI im. P.A. Gertsena – filial FGBU “NMITS radiologii” Minzdrava Rossii, 2022. 252 p. (In Russ.).
- Ishhenko K.B. Epidemiology, clinical picture and diagnosis of urothelial tumors of the renal pelvis and ureter: current state of the problem. Zlokachestvennye opukholi = Malignant Tumours 2016;2(18):66–71. (In Russ.). doi: 10.18027/2224-5057-2016-2-66-71
- Shariat S.F., Favaretto R.L., Gupta A. et al. Gender differences in radical nephroureterectomy for upper tract urothelial carcinoma. World J Urol 2011;29(4):481–6. doi: 10.1007/s00345-010-0594-7
- Rouprêt M., Babjuk M., Burger M. et al. Upper urinary tract urothelial cell carcinoma. European Association of Urology guidelines. Available at: https://uroweb.org/guideline/upperurinary-tract-urothelial-cell-carcinoma/
- O’Brien T., Ray E., Singh R. et al. Prevention of bladder tumours after nephroureterectomy for primary upper urinary tract urothelial carcinoma: a prospective, multicentre, randomised clinical trial of a single postoperative intravesical dose of mitomycin C (the ODMIT-C Trial). Eur Urol 2011;60(4):703–10. doi: 10.1016/j.eururo.2011.05.064
- Cutress M.L., Stewart G.D., Zakikhani P. et al. Ureteroscopic and percutaneous management of upper tract urothelial carcinoma (UTUC): systematic review. BJU Int 2012;110(5):614–28. doi: 10.1111/j.1464-410X.2012.11068.x
- Figurin K.M. Renal pelvic and ureteric malignancies. Onkourologiya = Cancer Urology 2006;2(2):5–12. (In Russ.). doi: 10.17650/1726-9776-2006-2-2-5-12
- Stepanova Yu.A., Prokofieva A.V., Dunaev S.A. et al. Upper tract urothelial carcinoma: morphology, diagnostics and treatment. Meditsinskaya vizualizatsiya = Medical Visualization 2018;22(1):78–92. (In Russ.). doi: 10.24835/1607-0763-2018-1-78-92
- Lopatkin N.A., Martov A.G., Ergakov D.V. Endoscopic techniques for diagnosis and treatment of papillary tumors of the upper urinary tract. Urologiia = Urology 2001;(3):46–51. (In Russ.).
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