Minimally invasive treatment of urothelial carcinoma of the upper urinary tract: clinical case

Cover Page

Cite item

Full Text

Abstract

Currently, the main approach to treatment of malignant tumors of the renal pelvis is radical nephroureterectomy. In some patient categories, organ-sparing surgeries are possible if several criteria are met. According to scientific publications, tumor recurrence and progression rates significantly vary in non-radical surgical treatment, and outcomes are contradictory. The article presents a clinical case of organ-sparing treatment of a young patient with progressive urothelial carcinoma.

About the authors

V. V. Protoshchak

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Author for correspondence.
Email: protoshakurology@mail.ru
ORCID iD: 0000-0002-4996-2927

Vladimir V. Protoshchak.

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

M. V. Paronnikov

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Email: paronnikov@mail.ru
ORCID iD: 0009-0005-1762-6100

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

E. G. Karpushchenko

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Email: Z_Karpushe@mail.ru
ORCID iD: 0000-0001-7464-5926
SPIN-code: 3753-4990

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

A. V. Sleptsov

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Email: slepzov_alive@mail.ru
ORCID iD: 0009-0009-2242-6858

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

P. A. Babkin

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

N. P. Kushnirenko

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

R. V. Novikov

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

ORCID iD: 0000-0003-1873-1293

6 Akademika Lebedeva St., Saint Petersburg 194044

Russian Federation

References

  1. Sung H., Ferlay J., Siegel R.L. et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021;71(3):209–49. doi: 10.3322/caac.21660
  2. National Cancer Institute. SEER Stat Fact Sheets: Bladder Cancer, 2015 Available at: http://seer.cancer.gov/statfacts/html/urinb.html [cited March 6, 2015].
  3. Cosentino M., Palou J., Gaya J.M. et al. Upper urinary tract urothelial cell carcinoma: location as a predictive factor for concomitant bladder carcinoma. World J Urol 2013;31(1):141–5. doi: 10.1007/s00345-012-0877-2
  4. Margulis V., Shariat S.F., Matin S.F. et al. Outcomes of radical nephroureterectomy: a series from the Upper Tract Urothelial Carcinoma Collaboration. Cancer 2009;115(6):1224–33. doi: 10.1002/cncr.24135
  5. Roupret M., Siesen T., Birtle A. et al. European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update. Eur Urol 2023;84(1):49–64. doi: 10.1016/j.eururo.2023.03.013
  6. Rosenthal D.L., Wojcik E.M., Kurtycz D.F.I. The Paris System for reporting urinary cytology. Springer, 2016.
  7. Martov A.G., Ergakov D.V., Andronov A.S. Upper tract urothelial carcinoma: can the tumor be removed en bloc? Onkourologiya = Cancer Urology 2022;18(3):123–7. (In Russ.). doi: 10.17650/1726-9776-2022-18-3-123-127
  8. Motamedinia P., Keheila M., Leavitt D.A. et al. The expanded use of percutaneous resection for upper tract urothelial carcinoma: a 30-year comprehensive experience. J Endourol 2016;30(3):262–7. doi: 10.1089/end.2015.0248
  9. Lucas S.M., Svatek R.S., Olgin G. et al. Conservative management in selected patients with upper tract urothelial carcinoma compares favourably with early radical surgery. BJU Int 2008;102(2):172–6. doi: 10.1111/j.1464-410X.2008.07535.x
  10. Belugina R., Kirsanov D., Protoshchak V. et al. Developing non-invasive bladder cancer screening methodology through potentiometric multisensor urine analysis. Talanta 2021;234:122696. doi: 10.1016/j.talanta.2021.122696
  11. Habuchi T., Takahashi R., Yamada H. et al. Metachronous multifocal development of urothelial cancers by intraluminal seeding. Lancet 1993;342(8879):1087–8. doi: 10.1016/0140-6736(93)92066-3
  12. Mistretta F.A., Carrion D.M., Nazzani S. et al. Bladder recurrence of primary upper tract urinary carcinoma following nephroureterectomy, and risk of upper urinary tract recurrence after ureteral stent positioning in patients with primary bladder cancer. Minerva Urol Nefrol 2019;71(3):191–200. doi: 10.23736/S0393-2249.19.03311-3
  13. Jones T.D., Wang M., Eble J.N. et al. Molecular evidence supporting field effect in urothelial carcinogenesis. Clin Cancer Res 2005;11(18):6512–9. doi: 10.1158/1078-0432.CCR-05-0891

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c)


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-36986 от  21.07.2009.