Metanephric adenoma of the kidney: clinical case and literature review

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Abstract

Metanephric adenoma is a rare benign kidney tumor with a favorable prognosis. These neoplasms are often interpreted as malignant at the preoperative stage, since they do not have specific characteristics showing during instrumental imaging methods, which leads to excessive surgical treatment in the context of nephrectomy volume. Therefore, histological verification is the gold standard for diagnosis. The morphological features of metanephric adenoma are in many ways similar to such kidney tumors as papillary renal cell carcinoma and nephroblastoma (Wilms’ tumor), so sometimes additional research methods are required, including immunohistochemical and molecular genetic ones. In this article, we report a rare clinical case of metanephric adenoma in a forty-seven-year-old woman. The results of clinical and instrumental exams, as well as morphological features of the tumor are presented. A review  of the literature on the clinical, morphological, and molecular aspects of this tumor is also presented.

About the authors

E. V. Grebenkin

UNIM; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)

Author for correspondence.
Email: grebenkin_urolog@mail.ru
ORCID iD: 0000-0002-4990-6722
SPIN-code: 6798-3427

Evgeniy V. Grebenkin.

Build. 6, 26 Podsosenskiy Pereulok, Moscow 101000; 31 Kashirskoe Shosse, Moscow 115409

Russian Federation

A. M. Pshikhachev

K+31 Clinic; M.V. Lomonosov Moscow State University

Email: pshich@yandex.ru
ORCID iD: 0000-0002-4424-3261
SPIN-code: 2256-7624

Build. 4, 42 Lobachevskogo St., Moscow 119415; Build. 1, 27 Lomonosovskiy Prospekt, Moscow 119192

Russian Federation

B. E. Osmolovskiy

K+31 Clinic

Email: borisosm@mail.ru
ORCID iD: 0009-0003-8562-1518
SPIN-code: 3092-9029

Build. 4, 42 Lobachevskogo St., Moscow 119415

Russian Federation

A. A. Epishkina

UNIM; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)

Email: afina-nn@mail.ru
ORCID iD: 0000-0002-7824-7949
SPIN-code: 6177-8262

Build. 6, 26 Podsosenskiy Pereulok, Moscow 101000; 31 Kashirskoe Shosse, Moscow 115409

Russian Federation

E. Yu. Kozhevnikova

UNIM

Email: shish300@mail.ru
ORCID iD: 0000-0001-5243-2479
SPIN-code: 5547-0248

Build. 6, 26 Podsosenskiy Pereulok, Moscow 101000

Russian Federation

N. I. Sorokin

M.V. Lomonosov Moscow State University

Email: nisorokin@mail.ru
ORCID iD: 0000-0001-9466-7567
SPIN-code: 8495-7626

Build. 1, 27 Lomonosovskiy Prospekt, Moscow 119192

Russian Federation

A. A. Kamalov

K+31 Clinic; M.V. Lomonosov Moscow State University

Email: armais.kamalov@rambler.ru
ORCID iD: 0000-0003-4251-7545
SPIN-code: 6609-5468

Build. 4, 42 Lobachevskogo St., Moscow 119415; Build. 1, 27 Lomonosovskiy Prospekt, Moscow 119192

Russian Federation

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