Solitary kidney cancer metastasis in the thoracic spine: case report

Cover Page

Cite item

Full Text

Abstract

Metastasis of kidney cancer to the bone tissue can be manifested through development of pathological fractures and spinal cord lesions. The clinical case of clear cell renal cell carcinoma with solitary metastasis in the thoracic spine presented in this article demonstrates the possibility of clinical manifestation of the disease through neurological symptoms and the importance of timely comprehensive diagnosis and adherence to treatment deadlines.

About the authors

S. A. Zamyatnin

Priozersk Interdistrict Hospital

Email: eiysium2000@mail.ru
ORCID iD: 0000-0002-8453-2148

35 Kalinina St., Priozersk, Leningrad region 188760

Russian Federation

I. S. Gonchar

Priozersk Interdistrict Hospital

Author for correspondence.
Email: Bonechka@mail.ru
ORCID iD: 0000-0003-1702-9849

Irina Sergeevna Gonchar 

35 Kalinina St., Priozersk, Leningrad region 188760

Russian Federation

References

  1. Santoni M., Conti A., Procopio G. et al. Bone metastases in patients with metastatic renal cell carcinoma: are they always associated with poor prognosis? J Exp Clin Cancer Res 2015;34(1):10. doi: 10.1186/s13046-015-0122-0
  2. Matveev V.B. Nivolumab as the new standard of metastatic kidney cancer treatment. Onkourologiya = Cancer Urology 2017;13(3): 18–26. (In Russ.). doi: 10.17650/1726-9776-2017-13-3-18-26
  3. Maslyakova G.N., Medvedeva A.V., Tsmokalyuk E.N. et al. The role of immunohistochemistry in diagnosis of different types of renal cell carcinoma. Bulleten meditsinskikh internet-konferentsiy = Bulletin of Medical Internet Conferences 2016;6(2):279–81. (In Russ.).
  4. Sanginov D.R., Zakiryakhodzhaev D.Z., Saidov Kh.M. Surgical tactics in renal cell carcinoma. Vestnik poslediplomnogo obrazovaniya v sfere zdravookhraneniya = Herald of Institute of Postgraduation Education in Health Sphere 2021;3:72–7. (In Russ.).
  5. Leon A., Pirasteh A., Costa D. Current challenges in diagnosis and assessment of the response of locally advanced and metastatic renal cell carcinoma. Radiographics 2019;39(4):998–1016. doi: 10.1148/rg.2019180178
  6. Yurmazov Z.A., Lushnikova N.A., Spirina L.V. et al. Capabilities of preoperative targeted therapy in treatment of bone metastases in renal cancer. Onkourologiya = Cancer Urology 2019;15(2): 35–41. (In Russ.). doi: 10.17650/1726-9776-2019-15-2-35-41
  7. Alyaev Yu.G., Sirota E.S., Bezrukov E.A. et al. Application of 3D soft print models of the kidney for treatment of patients with localized cancer of the kidney (a pilot study). Urologiya = Urоlogy 2017;(6):12–9. (In Russ.).
  8. Grunwald V., Eberhardt B., Bex A. et al. An interdisciplinary consensus on the management of bone metastases from renal cell carcinoma. Nat Rev Urol 2018;15(8):511–21. doi: 10.1038/s41585-018-0034-9
  9. Borisov P.S., Orlova R.V., Shkolnik M.I. et al. Efficacy of incomplete metastasectomy in combination with targeted therapy in metastatic kidney cancer patients. Onkourologiya = Cancer Urology 2019;15(4):65–72. (In Russ.). doi: 10.17650/1726-9776-2019-15-4-65-72
  10. Salapura V., Zupan I., Seruga B. et al. Osteoblastic bone metastases from renal cell carcinoma. Radiol Oncol 2014;48(3):243–6. doi: 10.2478/raon-2013-0034
  11. Borzov K.A., Valiev A.K., Musaev E.R. et al. Surgical treatment tactics for patients with metastases of renal cancer in the spine. Sarkomy kostey, myagkikh tkaney i opukholi kozhi = Bone and Soft Tissue Sarcomas, Tumors of the Skin 2018;(2):14–27. (In Russ.).
  12. Radchenko A.I., Zhukovec A.G., Bogdaev Ju.M. Surgical treatment for the solitary long bone metastasis from renal cell carcinoma. Onkologicheskiy zhurnal = Oncology Journal 2016;10(2(38)):50–6. (In Russ.).
  13. Dong S., Yang H., Tang Z. Development and validation of a predictive model to evaluate the risk of bone metastasis in kidney cancer. Front Oncol 2021;11:731905. doi: 10.3389/fonc.2021.731905
  14. Wood S.L., Brown J.E. Skeletal metastasis in renal cell carcinoma: current and future management options. Cancer Treat Rev 2012;38:284–91. doi: 10.1016/j.ctrv.2011.06.011
  15. Chen S., Kuo P. Bone metastasis from renal cell carcinoma. Int J Mol Sci 2016;17(6):987. doi: 10.3390/ijms17060987

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2022


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77-36986 от  21.07.2009.