Email this article Experience of Cancer Research Center in the treatment of advanced germ cell tumors
- Authors: Tyulyandin S.A.1, Tryakin A.A.1, Bulanov A.A.1, Figurin K.M.1, Fainshtein I.A.1, Polotskiy B.E.1, Mitin A.V.1, Zaharova T.I.1, Garin A.M.1
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Affiliations:
- ГУ РОНЦ им. Н.Н. Блохина РАМН
- Issue: Vol 1, No 3 (2005)
- Pages: 60-65
- Section: DIAGNOSIS AND TREATMENT OF URINARY SYSTEM TUMORS
- Published: 30.09.2005
- URL: https://oncourology.abvpress.ru/oncur/article/view/1204
- DOI: https://doi.org/10.17650/1726-9776-2005-1-3-60-65
- ID: 1204
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Abstract
The experience of CRC in the treatment of advanced germ cell tumors is reported. The analysis of factors influencing prognosis and treatment tactics is carried out. Contemporary conception of advanced germ cell tumors treatment implies the initial use of platinum based chemotherapy. After completion of chemotherapy, surgical removal of residual tumor (retroperitoneal and mediastinal lymph nodes, lung and liver metastases) carries diagnostic and curative means. Such approach allows curing 50-90% of patients depending on prognostic factors. Results of induction chemotherapy for relapses of germ cell tumors are presented separately. Treatment of this condition comprises chemotherapy with inclusion of ifosfamid or taxanes with following cytoreductive surgery. This modality allows long term remission in the fourth of patients with relapse of germ cell tumors.
About the authors
S. A. Tyulyandin
ГУ РОНЦ им. Н.Н. Блохина РАМН
Author for correspondence.
Russian Federation
A. A. Tryakin
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
A. A. Bulanov
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
K. M. Figurin
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
I. A. Fainshtein
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
B. E. Polotskiy
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
A. V. Mitin
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
T. I. Zaharova
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
A. M. Garin
ГУ РОНЦ им. Н.Н. Блохина РАМНRussian Federation
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