Organ-preserving treatment for renal cancer

Abstract

Оbjectives. To asses the direct results of surgical treatment of localized RCC with the help of NSS and RN, and to asses the possibilities of usage of domestic medication Perftoran with the aim of anti-ischemic protection.

Materials and Methods. 187 patients with localized RCC have been treated in our center for 5 years. 118 (63,1%) patients underwent RN and 69 (36,9%) underwent NSS. The mean age in the group of RN was 55,3 and NSS — 55,7. The mean size of the tumor in RN group was 37,91 mm and in the group NSS it was 29,86 mm. 47 patients (68,1%) had elective indications for NSS and 22 (31,9%) patients had imperative indications. Clamping renal artery was used with 21 patients, warm ischemia was used with 16 patients and cold ischemia was used in 5 cases. The mean duration of ischemia was 18,38 minutes. Perfusion of Perftoran was used through the renal artery.

Results. Post-operative mortality was noted in neither group. Early post-operative complications (within 30 days after the operation) in NSS group were noted with 10 patients. Those in RN group were noted with 1 patient. Reoperations were performed for 2 patients in NSS group and for 1 patient in RN group.

Conclusions. NSS is an effective means of control of RCC less than 4 cm with acceptable number of post-operative complications. We obtained good direct results using Perftoran for anti-ischemic protection.